Cargando…

GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS

Experimental infectious mouse hepatitis is associated with an increase in glutamic-oxaloacetic transaminase activity of the serum (SGO-T). A relationship appears to exist between the rise in SGO-T activity and (a) the size of the virus inoculum, (b) the blood virus titer, and (c) the degree of liver...

Descripción completa

Detalles Bibliográficos
Autores principales: Friend, Charlotte, Wróblewski, Felix, La Due, John S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1955
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136542/
https://www.ncbi.nlm.nih.gov/pubmed/13271682
_version_ 1782143143451295744
author Friend, Charlotte
Wróblewski, Felix
La Due, John S.
author_facet Friend, Charlotte
Wróblewski, Felix
La Due, John S.
author_sort Friend, Charlotte
collection PubMed
description Experimental infectious mouse hepatitis is associated with an increase in glutamic-oxaloacetic transaminase activity of the serum (SGO-T). A relationship appears to exist between the rise in SGO-T activity and (a) the size of the virus inoculum, (b) the blood virus titer, and (c) the degree of liver necrosis. Trauma to the liver following partial hepatectomy results in a rise in SGO-T activity in mice. Although mouse hepatitis differs from human hepatitis in the incubation period, histological changes, and natural course, both infections bring about comparable changes in SGO-T activity.
format Text
id pubmed-2136542
institution National Center for Biotechnology Information
language English
publishDate 1955
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21365422008-04-17 GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS Friend, Charlotte Wróblewski, Felix La Due, John S. J Exp Med Article Experimental infectious mouse hepatitis is associated with an increase in glutamic-oxaloacetic transaminase activity of the serum (SGO-T). A relationship appears to exist between the rise in SGO-T activity and (a) the size of the virus inoculum, (b) the blood virus titer, and (c) the degree of liver necrosis. Trauma to the liver following partial hepatectomy results in a rise in SGO-T activity in mice. Although mouse hepatitis differs from human hepatitis in the incubation period, histological changes, and natural course, both infections bring about comparable changes in SGO-T activity. The Rockefeller University Press 1955-11-30 /pmc/articles/PMC2136542/ /pubmed/13271682 Text en Copyright © Copyright, 1955, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Friend, Charlotte
Wróblewski, Felix
La Due, John S.
GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS
title GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS
title_full GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS
title_fullStr GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS
title_full_unstemmed GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS
title_short GLUTAMIC-OXALOACETIC TRANSAMINASE ACTIVITY OF SERUM IN MICE WITH VIRAL HEPATITIS
title_sort glutamic-oxaloacetic transaminase activity of serum in mice with viral hepatitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136542/
https://www.ncbi.nlm.nih.gov/pubmed/13271682
work_keys_str_mv AT friendcharlotte glutamicoxaloacetictransaminaseactivityofseruminmicewithviralhepatitis
AT wroblewskifelix glutamicoxaloacetictransaminaseactivityofseruminmicewithviralhepatitis
AT laduejohns glutamicoxaloacetictransaminaseactivityofseruminmicewithviralhepatitis