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GLOMERULONEPHRITIS PRODUCED IN DOGS BY SPECIFIC ANTISERA : II. PATHOLOGIC SEQUENCES FOLLOWING THE INJECTION OF RABBIT ANTIDOG-PLACENTA SERUM OR RABBIT ANTIDOG-KIDNEY SERUM

The intravenous injection of rabbit antidog-placenta or antidog-kidney serum produced immediate evidence of glomerulonephritis in dogs. The lesions produced by the two agents were indistinguishable. The glomerulonephritis so induced may terminate in death within 8 days, may progress to a chronic for...

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Detalles Bibliográficos
Autores principales: Bevans, Margaret, Seegal, Beatrice Carrier, Kaplan, Ruth
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1955
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136548/
https://www.ncbi.nlm.nih.gov/pubmed/13271691
Descripción
Sumario:The intravenous injection of rabbit antidog-placenta or antidog-kidney serum produced immediate evidence of glomerulonephritis in dogs. The lesions produced by the two agents were indistinguishable. The glomerulonephritis so induced may terminate in death within 8 days, may progress to a chronic form or may heal. The acute phase of the nephritis was usually associated with severe exudative and necrotizing renal lesions, while the pathologic sequences in surviving dogs were essentially reparative. However, 1 dog of 8 in the chronic phase developed a progressive chronic nephritis and died in uremia.