REDUCTION OF EXCESS CHOLESTEROL IN THE RABBIT AORTA BY INHIBITION OF ENDOGENOUS CHOLESTEROL SYNTHESIS

Hepatic cholesterol synthesis in rabbits, as measured by the incorporation of C(14)-labelled acetate, was inhibited by addition of non-toxic amounts of vanadyl sulfate (0.05 per cent VOSO(4)·2H(2)O) to the diet. This diet reduced excess aortic cholesterol in cholesterol prefed rabbits when fed durin...

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Detalles Bibliográficos
Autores principales: Curran, George L., Costello, Richard L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1956
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136554/
https://www.ncbi.nlm.nih.gov/pubmed/13278454
Descripción
Sumario:Hepatic cholesterol synthesis in rabbits, as measured by the incorporation of C(14)-labelled acetate, was inhibited by addition of non-toxic amounts of vanadyl sulfate (0.05 per cent VOSO(4)·2H(2)O) to the diet. This diet reduced excess aortic cholesterol in cholesterol prefed rabbits when fed during the 6 weeks immediately following a 4 week period of cholesterol feeding.

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