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COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERA
Passive oral immunization with O-antiserum was found to protect guinea pigs against fatal enteric cholera. The number of vibrios recoverable from the intestines of infected animals was not noticeably reduced by active and oral passive immunization. Passive immunization by the intraperitoneal route w...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1956
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136571/ https://www.ncbi.nlm.nih.gov/pubmed/13357694 |
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author | Freter, Rolf |
author_facet | Freter, Rolf |
author_sort | Freter, Rolf |
collection | PubMed |
description | Passive oral immunization with O-antiserum was found to protect guinea pigs against fatal enteric cholera. The number of vibrios recoverable from the intestines of infected animals was not noticeably reduced by active and oral passive immunization. Passive immunization by the intraperitoneal route was not protective even though high titers of circulating antibody were obtained shortly after injection. Oral administration of H-antiserum also had no protective effect. Introduction of E. coli into the intestinal tract increased the resistance of guinea pigs to fatal enteric cholera. |
format | Text |
id | pubmed-2136571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1956 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21365712008-04-17 COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERA Freter, Rolf J Exp Med Article Passive oral immunization with O-antiserum was found to protect guinea pigs against fatal enteric cholera. The number of vibrios recoverable from the intestines of infected animals was not noticeably reduced by active and oral passive immunization. Passive immunization by the intraperitoneal route was not protective even though high titers of circulating antibody were obtained shortly after injection. Oral administration of H-antiserum also had no protective effect. Introduction of E. coli into the intestinal tract increased the resistance of guinea pigs to fatal enteric cholera. The Rockefeller University Press 1956-09-01 /pmc/articles/PMC2136571/ /pubmed/13357694 Text en Copyright © Copyright, 1956, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Freter, Rolf COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERA |
title | COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERA |
title_full | COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERA |
title_fullStr | COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERA |
title_full_unstemmed | COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERA |
title_short | COPROANTIBODY AND BACTERIAL ANTAGONISM AS PROTECTIVE FACTORS IN EXPERIMENTAL ENTERIC CHOLERA |
title_sort | coproantibody and bacterial antagonism as protective factors in experimental enteric cholera |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136571/ https://www.ncbi.nlm.nih.gov/pubmed/13357694 |
work_keys_str_mv | AT freterrolf coproantibodyandbacterialantagonismasprotectivefactorsinexperimentalentericcholera |