ON THE NATURE OF PARABIOSIS INTOXICATION: SHOCK AS THE PRECIPITATING CAUSE

Spinal transection of one of a parabiotic pair of rats is immediately followed by a state indistinguishable in visual and hematologic characteristics from spontaneous "parabiosis intoxication." The transected rat develops erythremia, hyperhemoglobinemia, and an increased hematocrit count;...

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Detalles Bibliográficos
Autores principales: Hall, C. E., Hall, O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1956
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136580/
https://www.ncbi.nlm.nih.gov/pubmed/13286431
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author Hall, C. E.
Hall, O.
author_facet Hall, C. E.
Hall, O.
author_sort Hall, C. E.
collection PubMed
description Spinal transection of one of a parabiotic pair of rats is immediately followed by a state indistinguishable in visual and hematologic characteristics from spontaneous "parabiosis intoxication." The transected rat develops erythremia, hyperhemoglobinemia, and an increased hematocrit count; whereas the twin concurrently shows anemia characterized by a decrease in hemoglobin, erythrocyte count, and hematocrit reading, and often also lipemia. These findings are ascribed to whole blood transfusion of one rat by the other followed by adjustments compensatory to the resulting distortion in the respective blood volumes. It is suggested that parabiosis intoxication is a manifestation of this same process and is not due, as has been contended, to an immune response.
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spelling pubmed-21365802008-04-17 ON THE NATURE OF PARABIOSIS INTOXICATION: SHOCK AS THE PRECIPITATING CAUSE Hall, C. E. Hall, O. J Exp Med Article Spinal transection of one of a parabiotic pair of rats is immediately followed by a state indistinguishable in visual and hematologic characteristics from spontaneous "parabiosis intoxication." The transected rat develops erythremia, hyperhemoglobinemia, and an increased hematocrit count; whereas the twin concurrently shows anemia characterized by a decrease in hemoglobin, erythrocyte count, and hematocrit reading, and often also lipemia. These findings are ascribed to whole blood transfusion of one rat by the other followed by adjustments compensatory to the resulting distortion in the respective blood volumes. It is suggested that parabiosis intoxication is a manifestation of this same process and is not due, as has been contended, to an immune response. The Rockefeller University Press 1956-01-31 /pmc/articles/PMC2136580/ /pubmed/13286431 Text en Copyright © Copyright, 1956, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hall, C. E.
Hall, O.
ON THE NATURE OF PARABIOSIS INTOXICATION: SHOCK AS THE PRECIPITATING CAUSE
title ON THE NATURE OF PARABIOSIS INTOXICATION: SHOCK AS THE PRECIPITATING CAUSE
title_full ON THE NATURE OF PARABIOSIS INTOXICATION: SHOCK AS THE PRECIPITATING CAUSE
title_fullStr ON THE NATURE OF PARABIOSIS INTOXICATION: SHOCK AS THE PRECIPITATING CAUSE
title_full_unstemmed ON THE NATURE OF PARABIOSIS INTOXICATION: SHOCK AS THE PRECIPITATING CAUSE
title_short ON THE NATURE OF PARABIOSIS INTOXICATION: SHOCK AS THE PRECIPITATING CAUSE
title_sort on the nature of parabiosis intoxication: shock as the precipitating cause
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136580/
https://www.ncbi.nlm.nih.gov/pubmed/13286431
work_keys_str_mv AT hallce onthenatureofparabiosisintoxicationshockastheprecipitatingcause
AT hallo onthenatureofparabiosisintoxicationshockastheprecipitatingcause

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