THE PATHOGENESIS OF HYPERLIPEMIA INDUCED BY MEANS OF SURFACE-ACTIVE AGENTS : I. INCREASED TOTAL BODY CHOLESTEROL IN MICE GIVEN TRITON WR 1339 PARENTERALLY

Mice rendered hyperlipemic by means of intravenous or subcutaneous injections of triton WR 1339 were found to have an increase in the total amount of cholesterol in their bodies. This observation indicates that the injected surface-active agent affects the metabolism of cholesterol and brings about...

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Detalles Bibliográficos
Autores principales: Hirsch, Robert L., Kellner, Aaron
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1956
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136643/
https://www.ncbi.nlm.nih.gov/pubmed/13332176
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author Hirsch, Robert L.
Kellner, Aaron
author_facet Hirsch, Robert L.
Kellner, Aaron
author_sort Hirsch, Robert L.
collection PubMed
description Mice rendered hyperlipemic by means of intravenous or subcutaneous injections of triton WR 1339 were found to have an increase in the total amount of cholesterol in their bodies. This observation indicates that the injected surface-active agent affects the metabolism of cholesterol and brings about hyperlipemia by augmenting the synthesis of lipides, or by interfering with their degradation or excretion, or by some combination of these factors. The implications of the findings for the pathogenesis of the hyperlipemia induced by triton are discussed further in the accompanying paper (16).
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spelling pubmed-21366432008-04-17 THE PATHOGENESIS OF HYPERLIPEMIA INDUCED BY MEANS OF SURFACE-ACTIVE AGENTS : I. INCREASED TOTAL BODY CHOLESTEROL IN MICE GIVEN TRITON WR 1339 PARENTERALLY Hirsch, Robert L. Kellner, Aaron J Exp Med Article Mice rendered hyperlipemic by means of intravenous or subcutaneous injections of triton WR 1339 were found to have an increase in the total amount of cholesterol in their bodies. This observation indicates that the injected surface-active agent affects the metabolism of cholesterol and brings about hyperlipemia by augmenting the synthesis of lipides, or by interfering with their degradation or excretion, or by some combination of these factors. The implications of the findings for the pathogenesis of the hyperlipemia induced by triton are discussed further in the accompanying paper (16). The Rockefeller University Press 1956-07-01 /pmc/articles/PMC2136643/ /pubmed/13332176 Text en Copyright © Copyright, 1956, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hirsch, Robert L.
Kellner, Aaron
THE PATHOGENESIS OF HYPERLIPEMIA INDUCED BY MEANS OF SURFACE-ACTIVE AGENTS : I. INCREASED TOTAL BODY CHOLESTEROL IN MICE GIVEN TRITON WR 1339 PARENTERALLY
title THE PATHOGENESIS OF HYPERLIPEMIA INDUCED BY MEANS OF SURFACE-ACTIVE AGENTS : I. INCREASED TOTAL BODY CHOLESTEROL IN MICE GIVEN TRITON WR 1339 PARENTERALLY
title_full THE PATHOGENESIS OF HYPERLIPEMIA INDUCED BY MEANS OF SURFACE-ACTIVE AGENTS : I. INCREASED TOTAL BODY CHOLESTEROL IN MICE GIVEN TRITON WR 1339 PARENTERALLY
title_fullStr THE PATHOGENESIS OF HYPERLIPEMIA INDUCED BY MEANS OF SURFACE-ACTIVE AGENTS : I. INCREASED TOTAL BODY CHOLESTEROL IN MICE GIVEN TRITON WR 1339 PARENTERALLY
title_full_unstemmed THE PATHOGENESIS OF HYPERLIPEMIA INDUCED BY MEANS OF SURFACE-ACTIVE AGENTS : I. INCREASED TOTAL BODY CHOLESTEROL IN MICE GIVEN TRITON WR 1339 PARENTERALLY
title_short THE PATHOGENESIS OF HYPERLIPEMIA INDUCED BY MEANS OF SURFACE-ACTIVE AGENTS : I. INCREASED TOTAL BODY CHOLESTEROL IN MICE GIVEN TRITON WR 1339 PARENTERALLY
title_sort pathogenesis of hyperlipemia induced by means of surface-active agents : i. increased total body cholesterol in mice given triton wr 1339 parenterally
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136643/
https://www.ncbi.nlm.nih.gov/pubmed/13332176
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