IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS

Evidence has been provided that a state of irreversible hemorrhagic shock can be induced in a bacteria-free environment in rats reared under germfree conditions. The response to bleeding, the duration of the hypotensive episode and the pathological changes were the same in the germfree and in normal...

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Detalles Bibliográficos
Autores principales: Zweifach, B. W., Gordon, H. A., Wagner, M., Reyniers, J. A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1958
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136688/
https://www.ncbi.nlm.nih.gov/pubmed/13513911
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author Zweifach, B. W.
Gordon, H. A.
Wagner, M.
Reyniers, J. A.
author_facet Zweifach, B. W.
Gordon, H. A.
Wagner, M.
Reyniers, J. A.
author_sort Zweifach, B. W.
collection PubMed
description Evidence has been provided that a state of irreversible hemorrhagic shock can be induced in a bacteria-free environment in rats reared under germfree conditions. The response to bleeding, the duration of the hypotensive episode and the pathological changes were the same in the germfree and in normal stock rats. The findings are interpreted as evidence opposed to the concept that bacteria or bacterial products are implicated, as primary factors, in the pathogenicity of shock.
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spelling pubmed-21366882008-04-17 IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS Zweifach, B. W. Gordon, H. A. Wagner, M. Reyniers, J. A. J Exp Med Article Evidence has been provided that a state of irreversible hemorrhagic shock can be induced in a bacteria-free environment in rats reared under germfree conditions. The response to bleeding, the duration of the hypotensive episode and the pathological changes were the same in the germfree and in normal stock rats. The findings are interpreted as evidence opposed to the concept that bacteria or bacterial products are implicated, as primary factors, in the pathogenicity of shock. The Rockefeller University Press 1958-02-28 /pmc/articles/PMC2136688/ /pubmed/13513911 Text en Copyright © Copyright, 1958, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Zweifach, B. W.
Gordon, H. A.
Wagner, M.
Reyniers, J. A.
IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS
title IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS
title_full IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS
title_fullStr IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS
title_full_unstemmed IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS
title_short IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS
title_sort irreversible hemorrhagic shock in germfree rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136688/
https://www.ncbi.nlm.nih.gov/pubmed/13513911
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