CORTICOTROPINS (ACTH) : X. BIOLOGICAL INVESTIGATIONS ONα-CORTICOTROPIN

Purified α-corticotropin has been reported to exercise the following biological effects: (a) stimulation of the adrenal glands in normal and hypophysectomized rats, (b) production of blood eosinopenia in hypophysectomized rats, (c) maintenance of muscle glycogen in hypophysectomized rats, (d) inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Choh Hao, Fønss-Bech, Peter, Geschwind, Irving I., Hayashida, Tetsuo, Hungerford, Gerald F., Lostroh, Ardis J., Lyons, William R., Moon, Henry D., Reinhardt, William O., Sideman, Martin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1957
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136701/
https://www.ncbi.nlm.nih.gov/pubmed/13416472
_version_ 1782143180970393600
author Li, Choh Hao
Fønss-Bech, Peter
Geschwind, Irving I.
Hayashida, Tetsuo
Hungerford, Gerald F.
Lostroh, Ardis J.
Lyons, William R.
Moon, Henry D.
Reinhardt, William O.
Sideman, Martin
author_facet Li, Choh Hao
Fønss-Bech, Peter
Geschwind, Irving I.
Hayashida, Tetsuo
Hungerford, Gerald F.
Lostroh, Ardis J.
Lyons, William R.
Moon, Henry D.
Reinhardt, William O.
Sideman, Martin
author_sort Li, Choh Hao
collection PubMed
description Purified α-corticotropin has been reported to exercise the following biological effects: (a) stimulation of the adrenal glands in normal and hypophysectomized rats, (b) production of blood eosinopenia in hypophysectomized rats, (c) maintenance of muscle glycogen in hypophysectomized rats, (d) inhibition of growth-promoting activity of somatotropin, (e) stimulation of melanocytes in the skin of frogs, (f) mobilization of fat into the liver of fasted mice, (g) stimulation of the accessory sex glands of castrated-hypophysectomized male rats, (h) induction of deciduoma formation in hypophysectomized-oophorectomized rats, and (i) elevation of the total red cell volume in hypophysectomized rats. α-Corticotropin has also been shown for the first time to act in synergism with lactogenic hormone as an essential galactopoietic hormone. The ability of α-corticotropin to elicit biological responses in the absence of the adrenal cortex is discussed.
format Text
id pubmed-2136701
institution National Center for Biotechnology Information
language English
publishDate 1957
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21367012008-04-17 CORTICOTROPINS (ACTH) : X. BIOLOGICAL INVESTIGATIONS ONα-CORTICOTROPIN Li, Choh Hao Fønss-Bech, Peter Geschwind, Irving I. Hayashida, Tetsuo Hungerford, Gerald F. Lostroh, Ardis J. Lyons, William R. Moon, Henry D. Reinhardt, William O. Sideman, Martin J Exp Med Article Purified α-corticotropin has been reported to exercise the following biological effects: (a) stimulation of the adrenal glands in normal and hypophysectomized rats, (b) production of blood eosinopenia in hypophysectomized rats, (c) maintenance of muscle glycogen in hypophysectomized rats, (d) inhibition of growth-promoting activity of somatotropin, (e) stimulation of melanocytes in the skin of frogs, (f) mobilization of fat into the liver of fasted mice, (g) stimulation of the accessory sex glands of castrated-hypophysectomized male rats, (h) induction of deciduoma formation in hypophysectomized-oophorectomized rats, and (i) elevation of the total red cell volume in hypophysectomized rats. α-Corticotropin has also been shown for the first time to act in synergism with lactogenic hormone as an essential galactopoietic hormone. The ability of α-corticotropin to elicit biological responses in the absence of the adrenal cortex is discussed. The Rockefeller University Press 1957-03-31 /pmc/articles/PMC2136701/ /pubmed/13416472 Text en Copyright © Copyright, 1957, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Li, Choh Hao
Fønss-Bech, Peter
Geschwind, Irving I.
Hayashida, Tetsuo
Hungerford, Gerald F.
Lostroh, Ardis J.
Lyons, William R.
Moon, Henry D.
Reinhardt, William O.
Sideman, Martin
CORTICOTROPINS (ACTH) : X. BIOLOGICAL INVESTIGATIONS ONα-CORTICOTROPIN
title CORTICOTROPINS (ACTH) : X. BIOLOGICAL INVESTIGATIONS ONα-CORTICOTROPIN
title_full CORTICOTROPINS (ACTH) : X. BIOLOGICAL INVESTIGATIONS ONα-CORTICOTROPIN
title_fullStr CORTICOTROPINS (ACTH) : X. BIOLOGICAL INVESTIGATIONS ONα-CORTICOTROPIN
title_full_unstemmed CORTICOTROPINS (ACTH) : X. BIOLOGICAL INVESTIGATIONS ONα-CORTICOTROPIN
title_short CORTICOTROPINS (ACTH) : X. BIOLOGICAL INVESTIGATIONS ONα-CORTICOTROPIN
title_sort corticotropins (acth) : x. biological investigations onα-corticotropin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136701/
https://www.ncbi.nlm.nih.gov/pubmed/13416472
work_keys_str_mv AT lichohhao corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT fønssbechpeter corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT geschwindirvingi corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT hayashidatetsuo corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT hungerfordgeraldf corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT lostrohardisj corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT lyonswilliamr corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT moonhenryd corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT reinhardtwilliamo corticotropinsacthxbiologicalinvestigationsonacorticotropin
AT sidemanmartin corticotropinsacthxbiologicalinvestigationsonacorticotropin

Ejemplares similares