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STUDIES OF THE PLASMIN SYSTEM : I. MEASUREMENT OF HUMAN AND ANIMAL PLASMINOGEN. MEASUREMENT OF AN ACTIVATOR IN HUMAN SERUM
A general assay method involving casein digestion is shown to be applicable for determination of several components of the plasmin system. Total plasminogen of human serum can be measured by use of sufficient streptokinase for instantaneous activation, accompanied by protection of the active plasmin...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1957
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136775/ https://www.ncbi.nlm.nih.gov/pubmed/13463252 |
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author | Norman, Philip S. |
author_facet | Norman, Philip S. |
author_sort | Norman, Philip S. |
collection | PubMed |
description | A general assay method involving casein digestion is shown to be applicable for determination of several components of the plasmin system. Total plasminogen of human serum can be measured by use of sufficient streptokinase for instantaneous activation, accompanied by protection of the active plasmin with casein. Total plasminogen of guinea pig serum can be measured after complete activation with streptokinase in combination with human activator. The activator principle in whole human serum can be measured by its ability to activate guinea pig plasminogen. |
format | Text |
id | pubmed-2136775 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1957 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21367752008-04-17 STUDIES OF THE PLASMIN SYSTEM : I. MEASUREMENT OF HUMAN AND ANIMAL PLASMINOGEN. MEASUREMENT OF AN ACTIVATOR IN HUMAN SERUM Norman, Philip S. J Exp Med Article A general assay method involving casein digestion is shown to be applicable for determination of several components of the plasmin system. Total plasminogen of human serum can be measured by use of sufficient streptokinase for instantaneous activation, accompanied by protection of the active plasmin with casein. Total plasminogen of guinea pig serum can be measured after complete activation with streptokinase in combination with human activator. The activator principle in whole human serum can be measured by its ability to activate guinea pig plasminogen. The Rockefeller University Press 1957-09-01 /pmc/articles/PMC2136775/ /pubmed/13463252 Text en Copyright © Copyright, 1957, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Norman, Philip S. STUDIES OF THE PLASMIN SYSTEM : I. MEASUREMENT OF HUMAN AND ANIMAL PLASMINOGEN. MEASUREMENT OF AN ACTIVATOR IN HUMAN SERUM |
title | STUDIES OF THE PLASMIN SYSTEM : I. MEASUREMENT OF HUMAN AND ANIMAL PLASMINOGEN. MEASUREMENT OF AN ACTIVATOR IN HUMAN SERUM |
title_full | STUDIES OF THE PLASMIN SYSTEM : I. MEASUREMENT OF HUMAN AND ANIMAL PLASMINOGEN. MEASUREMENT OF AN ACTIVATOR IN HUMAN SERUM |
title_fullStr | STUDIES OF THE PLASMIN SYSTEM : I. MEASUREMENT OF HUMAN AND ANIMAL PLASMINOGEN. MEASUREMENT OF AN ACTIVATOR IN HUMAN SERUM |
title_full_unstemmed | STUDIES OF THE PLASMIN SYSTEM : I. MEASUREMENT OF HUMAN AND ANIMAL PLASMINOGEN. MEASUREMENT OF AN ACTIVATOR IN HUMAN SERUM |
title_short | STUDIES OF THE PLASMIN SYSTEM : I. MEASUREMENT OF HUMAN AND ANIMAL PLASMINOGEN. MEASUREMENT OF AN ACTIVATOR IN HUMAN SERUM |
title_sort | studies of the plasmin system : i. measurement of human and animal plasminogen. measurement of an activator in human serum |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136775/ https://www.ncbi.nlm.nih.gov/pubmed/13463252 |
work_keys_str_mv | AT normanphilips studiesoftheplasminsystemimeasurementofhumanandanimalplasminogenmeasurementofanactivatorinhumanserum |