STUDIES ON THE EFFECT OF TRITON (WR-1339) ON GUINEA PIG TISSUES : III. TUBERCULIN HYPERSENSITIVITY AND IN VITRO CYTOLYSIS OF LEUCOCYTES BY TUBERCULIN

The administration of triton WR-1339 (300 mg./kg. subcutaneously) to tuberculin-sensitive guinea pigs 2 hours before the intradermal injection of PPD depresses slightly their skin sensitivity to tuberculin and essentially obliterates the lytic effect of tuberculin on their circulating leucocytes. Wh...

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Detalles Bibliográficos
Autores principales: Patnode, Robert A., Hudgins, Paul C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1958
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136785/
https://www.ncbi.nlm.nih.gov/pubmed/13481255
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author Patnode, Robert A.
Hudgins, Paul C.
author_facet Patnode, Robert A.
Hudgins, Paul C.
author_sort Patnode, Robert A.
collection PubMed
description The administration of triton WR-1339 (300 mg./kg. subcutaneously) to tuberculin-sensitive guinea pigs 2 hours before the intradermal injection of PPD depresses slightly their skin sensitivity to tuberculin and essentially obliterates the lytic effect of tuberculin on their circulating leucocytes. When leucocytes from tuberculin-sensitive guinea pigs are exposed to triton in vitro at a concentration level attainable in vivo the cells are partially protected against lysis by PPD.
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spelling pubmed-21367852008-04-17 STUDIES ON THE EFFECT OF TRITON (WR-1339) ON GUINEA PIG TISSUES : III. TUBERCULIN HYPERSENSITIVITY AND IN VITRO CYTOLYSIS OF LEUCOCYTES BY TUBERCULIN Patnode, Robert A. Hudgins, Paul C. J Exp Med Article The administration of triton WR-1339 (300 mg./kg. subcutaneously) to tuberculin-sensitive guinea pigs 2 hours before the intradermal injection of PPD depresses slightly their skin sensitivity to tuberculin and essentially obliterates the lytic effect of tuberculin on their circulating leucocytes. When leucocytes from tuberculin-sensitive guinea pigs are exposed to triton in vitro at a concentration level attainable in vivo the cells are partially protected against lysis by PPD. The Rockefeller University Press 1958-01-01 /pmc/articles/PMC2136785/ /pubmed/13481255 Text en Copyright © Copyright, 1958, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Patnode, Robert A.
Hudgins, Paul C.
STUDIES ON THE EFFECT OF TRITON (WR-1339) ON GUINEA PIG TISSUES : III. TUBERCULIN HYPERSENSITIVITY AND IN VITRO CYTOLYSIS OF LEUCOCYTES BY TUBERCULIN
title STUDIES ON THE EFFECT OF TRITON (WR-1339) ON GUINEA PIG TISSUES : III. TUBERCULIN HYPERSENSITIVITY AND IN VITRO CYTOLYSIS OF LEUCOCYTES BY TUBERCULIN
title_full STUDIES ON THE EFFECT OF TRITON (WR-1339) ON GUINEA PIG TISSUES : III. TUBERCULIN HYPERSENSITIVITY AND IN VITRO CYTOLYSIS OF LEUCOCYTES BY TUBERCULIN
title_fullStr STUDIES ON THE EFFECT OF TRITON (WR-1339) ON GUINEA PIG TISSUES : III. TUBERCULIN HYPERSENSITIVITY AND IN VITRO CYTOLYSIS OF LEUCOCYTES BY TUBERCULIN
title_full_unstemmed STUDIES ON THE EFFECT OF TRITON (WR-1339) ON GUINEA PIG TISSUES : III. TUBERCULIN HYPERSENSITIVITY AND IN VITRO CYTOLYSIS OF LEUCOCYTES BY TUBERCULIN
title_short STUDIES ON THE EFFECT OF TRITON (WR-1339) ON GUINEA PIG TISSUES : III. TUBERCULIN HYPERSENSITIVITY AND IN VITRO CYTOLYSIS OF LEUCOCYTES BY TUBERCULIN
title_sort studies on the effect of triton (wr-1339) on guinea pig tissues : iii. tuberculin hypersensitivity and in vitro cytolysis of leucocytes by tuberculin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136785/
https://www.ncbi.nlm.nih.gov/pubmed/13481255
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AT hudginspaulc studiesontheeffectoftritonwr1339onguineapigtissuesiiituberculinhypersensitivityandinvitrocytolysisofleucocytesbytuberculin

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