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DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST

In further study of streptococci having the R antigen, the bactericidal test has been used instead of the mouse protection test in investigating the type-specific M antigens of these organisms. The results have been confirmed by M anti-M precipitin tests, and a correlation between the M and T antige...

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Detalles Bibliográficos
Autor principal: Lancefield, Rebecca C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1957
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136803/
https://www.ncbi.nlm.nih.gov/pubmed/13475611
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author Lancefield, Rebecca C.
author_facet Lancefield, Rebecca C.
author_sort Lancefield, Rebecca C.
collection PubMed
description In further study of streptococci having the R antigen, the bactericidal test has been used instead of the mouse protection test in investigating the type-specific M antigens of these organisms. The results have been confirmed by M anti-M precipitin tests, and a correlation between the M and T antigens of the strains has been shown. On the basis of a specific M antigen, type 28 has been shown to comprise Griffith's strain Small and four other R-containing strains. A number of other strains previously thought to belong to type 28 on the basis of R antigen reactions have now been identified as belonging either to type 2 or to a new type, designated 48, which shows a one-way cross-relationship to type 13. The bactericidal test is suggested as a useful method for assessing M antigen in group A streptococci and for establishing type-specificity by means of a biological test which is more widely applicable than the standard mouse protection test.
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spelling pubmed-21368032008-04-17 DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST Lancefield, Rebecca C. J Exp Med Article In further study of streptococci having the R antigen, the bactericidal test has been used instead of the mouse protection test in investigating the type-specific M antigens of these organisms. The results have been confirmed by M anti-M precipitin tests, and a correlation between the M and T antigens of the strains has been shown. On the basis of a specific M antigen, type 28 has been shown to comprise Griffith's strain Small and four other R-containing strains. A number of other strains previously thought to belong to type 28 on the basis of R antigen reactions have now been identified as belonging either to type 2 or to a new type, designated 48, which shows a one-way cross-relationship to type 13. The bactericidal test is suggested as a useful method for assessing M antigen in group A streptococci and for establishing type-specificity by means of a biological test which is more widely applicable than the standard mouse protection test. The Rockefeller University Press 1957-09-30 /pmc/articles/PMC2136803/ /pubmed/13475611 Text en Copyright © Copyright, 1957, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lancefield, Rebecca C.
DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST
title DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST
title_full DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST
title_fullStr DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST
title_full_unstemmed DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST
title_short DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST
title_sort differentiation of group a streptococci with a common r antigen into three serological types, with special reference to the bactericidal test
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136803/
https://www.ncbi.nlm.nih.gov/pubmed/13475611
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