MACROGLOBULINEMIA : I. THE ANTIGENIC RELATIONSHIP OF PATHOLOGICAL MACROGLOBULINS TO NORMALγ-GLOBULINS

Highly purified pathological macroglobulins, which had been characterized electrophoretically and in the ultracentrifuge, were studied by the Ouchterlony gel diffusion technique. These macroglobulins were shown to be antigenically related to normal γ(1)-macroglobulin (19S) as well as the 7S γ-globul...

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Detalles Bibliográficos
Autores principales: Korngold, Leonhard, Van Leeuwen, Gerda
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1957
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136814/
https://www.ncbi.nlm.nih.gov/pubmed/13475606
Descripción
Sumario:Highly purified pathological macroglobulins, which had been characterized electrophoretically and in the ultracentrifuge, were studied by the Ouchterlony gel diffusion technique. These macroglobulins were shown to be antigenically related to normal γ(1)-macroglobulin (19S) as well as the 7S γ-globulins. The pathological macroglobulins differ among each other and they are antigenically deficient when compared with the normal macroglobulin. There is no correlation between the macroglobulin's antigenic structure and its physico-chemical properties.

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