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ADSORPTION AND MATURATION OF POLIOVIRUS IN SINGLY AND MULTIPLY INFECTED HELA CELLS
Studies with polio-infected HeLa cells using cell disruption techniques during the early stages of infection have shown that: The inoculum of poliovirus adsorbed on HeLa cells is largely inactivated. Infective virus accumulates in a monolayer sheet of cells in advance of release into the medium. The...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1958
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136847/ https://www.ncbi.nlm.nih.gov/pubmed/13525575 |
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author | Darnell, James E. |
author_facet | Darnell, James E. |
author_sort | Darnell, James E. |
collection | PubMed |
description | Studies with polio-infected HeLa cells using cell disruption techniques during the early stages of infection have shown that: The inoculum of poliovirus adsorbed on HeLa cells is largely inactivated. Infective virus accumulates in a monolayer sheet of cells in advance of release into the medium. The eclipse period is shorter in multiply infected cells than in those infected with a single particle. |
format | Text |
id | pubmed-2136847 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1958 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21368472008-04-17 ADSORPTION AND MATURATION OF POLIOVIRUS IN SINGLY AND MULTIPLY INFECTED HELA CELLS Darnell, James E. J Exp Med Article Studies with polio-infected HeLa cells using cell disruption techniques during the early stages of infection have shown that: The inoculum of poliovirus adsorbed on HeLa cells is largely inactivated. Infective virus accumulates in a monolayer sheet of cells in advance of release into the medium. The eclipse period is shorter in multiply infected cells than in those infected with a single particle. The Rockefeller University Press 1958-05-01 /pmc/articles/PMC2136847/ /pubmed/13525575 Text en Copyright © Copyright, 1958, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Darnell, James E. ADSORPTION AND MATURATION OF POLIOVIRUS IN SINGLY AND MULTIPLY INFECTED HELA CELLS |
title | ADSORPTION AND MATURATION OF POLIOVIRUS IN SINGLY AND MULTIPLY INFECTED HELA CELLS |
title_full | ADSORPTION AND MATURATION OF POLIOVIRUS IN SINGLY AND MULTIPLY INFECTED HELA CELLS |
title_fullStr | ADSORPTION AND MATURATION OF POLIOVIRUS IN SINGLY AND MULTIPLY INFECTED HELA CELLS |
title_full_unstemmed | ADSORPTION AND MATURATION OF POLIOVIRUS IN SINGLY AND MULTIPLY INFECTED HELA CELLS |
title_short | ADSORPTION AND MATURATION OF POLIOVIRUS IN SINGLY AND MULTIPLY INFECTED HELA CELLS |
title_sort | adsorption and maturation of poliovirus in singly and multiply infected hela cells |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136847/ https://www.ncbi.nlm.nih.gov/pubmed/13525575 |
work_keys_str_mv | AT darnelljamese adsorptionandmaturationofpoliovirusinsinglyandmultiplyinfectedhelacells |