Cargando…
FOLINIC ACID AND NON-DIALYZABLE MATERIALS IN THE NUTRITION OF MALARIA PARASITES
The extracellular survival of the malaria parasite Plasmodium lophurae was favored on the 4th day of incubation in vitro by the presence in the medium of added folinic acid at a concentration of about 5 µg. per ml. The development of the human malaria parasite P. falciparum intracellularly in suspen...
Autor principal: | |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1958
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136905/ https://www.ncbi.nlm.nih.gov/pubmed/13587855 |
_version_ | 1782143228943794176 |
---|---|
author | Trager, William |
author_facet | Trager, William |
author_sort | Trager, William |
collection | PubMed |
description | The extracellular survival of the malaria parasite Plasmodium lophurae was favored on the 4th day of incubation in vitro by the presence in the medium of added folinic acid at a concentration of about 5 µg. per ml. The development of the human malaria parasite P. falciparum intracellularly in suspensions of human erythrocytes was better in a medium with a high than in one with a low concentration of folic acid. In the early extracellular development of P. lophurae in vitro erythrocyte extract could be partially replaced by certain yeast protein preparations and by a non-dialyzable fraction, free from hemoglobin, prepared from duck erythrocyte extract by means of starch electrophoresis. |
format | Text |
id | pubmed-2136905 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1958 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21369052008-04-17 FOLINIC ACID AND NON-DIALYZABLE MATERIALS IN THE NUTRITION OF MALARIA PARASITES Trager, William J Exp Med Article The extracellular survival of the malaria parasite Plasmodium lophurae was favored on the 4th day of incubation in vitro by the presence in the medium of added folinic acid at a concentration of about 5 µg. per ml. The development of the human malaria parasite P. falciparum intracellularly in suspensions of human erythrocytes was better in a medium with a high than in one with a low concentration of folic acid. In the early extracellular development of P. lophurae in vitro erythrocyte extract could be partially replaced by certain yeast protein preparations and by a non-dialyzable fraction, free from hemoglobin, prepared from duck erythrocyte extract by means of starch electrophoresis. The Rockefeller University Press 1958-10-31 /pmc/articles/PMC2136905/ /pubmed/13587855 Text en Copyright © Copyright, 1958, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Trager, William FOLINIC ACID AND NON-DIALYZABLE MATERIALS IN THE NUTRITION OF MALARIA PARASITES |
title | FOLINIC ACID AND NON-DIALYZABLE MATERIALS IN THE NUTRITION OF MALARIA PARASITES |
title_full | FOLINIC ACID AND NON-DIALYZABLE MATERIALS IN THE NUTRITION OF MALARIA PARASITES |
title_fullStr | FOLINIC ACID AND NON-DIALYZABLE MATERIALS IN THE NUTRITION OF MALARIA PARASITES |
title_full_unstemmed | FOLINIC ACID AND NON-DIALYZABLE MATERIALS IN THE NUTRITION OF MALARIA PARASITES |
title_short | FOLINIC ACID AND NON-DIALYZABLE MATERIALS IN THE NUTRITION OF MALARIA PARASITES |
title_sort | folinic acid and non-dialyzable materials in the nutrition of malaria parasites |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136905/ https://www.ncbi.nlm.nih.gov/pubmed/13587855 |
work_keys_str_mv | AT tragerwilliam folinicacidandnondialyzablematerialsinthenutritionofmalariaparasites |