POLIOMYELITIS AS A COMPLEX INFECTION

Young cynomolgus monkeys inoculated intracerebrally with an attenuated Type 1 polio virus and, after 5 days, with a monkey adapted Coxsackie A-14 virus frequently became paralyzed. Neither virus alone was capable of inducing paralysis. Similar results were observed when the AB IV strain of Coxsackie...

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Detalles Bibliográficos
Autores principales: Dalldorf, Gilbert, Weigand, Heribert
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1958
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136911/
https://www.ncbi.nlm.nih.gov/pubmed/13587845
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author Dalldorf, Gilbert
Weigand, Heribert
author_facet Dalldorf, Gilbert
Weigand, Heribert
author_sort Dalldorf, Gilbert
collection PubMed
description Young cynomolgus monkeys inoculated intracerebrally with an attenuated Type 1 polio virus and, after 5 days, with a monkey adapted Coxsackie A-14 virus frequently became paralyzed. Neither virus alone was capable of inducing paralysis. Similar results were observed when the AB IV strain of Coxsackie A-7 was substituted for the A-14 virus. In this case the 2nd inoculation was made intramuscularly. Paralytic poliomyelitis may at times represent the summation of two infections, the total of motor neuron destruction by two independent and noninterfering enteroviruses.
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spelling pubmed-21369112008-04-17 POLIOMYELITIS AS A COMPLEX INFECTION Dalldorf, Gilbert Weigand, Heribert J Exp Med Article Young cynomolgus monkeys inoculated intracerebrally with an attenuated Type 1 polio virus and, after 5 days, with a monkey adapted Coxsackie A-14 virus frequently became paralyzed. Neither virus alone was capable of inducing paralysis. Similar results were observed when the AB IV strain of Coxsackie A-7 was substituted for the A-14 virus. In this case the 2nd inoculation was made intramuscularly. Paralytic poliomyelitis may at times represent the summation of two infections, the total of motor neuron destruction by two independent and noninterfering enteroviruses. The Rockefeller University Press 1958-10-31 /pmc/articles/PMC2136911/ /pubmed/13587845 Text en Copyright © Copyright, 1958, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dalldorf, Gilbert
Weigand, Heribert
POLIOMYELITIS AS A COMPLEX INFECTION
title POLIOMYELITIS AS A COMPLEX INFECTION
title_full POLIOMYELITIS AS A COMPLEX INFECTION
title_fullStr POLIOMYELITIS AS A COMPLEX INFECTION
title_full_unstemmed POLIOMYELITIS AS A COMPLEX INFECTION
title_short POLIOMYELITIS AS A COMPLEX INFECTION
title_sort poliomyelitis as a complex infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136911/
https://www.ncbi.nlm.nih.gov/pubmed/13587845
work_keys_str_mv AT dalldorfgilbert poliomyelitisasacomplexinfection
AT weigandheribert poliomyelitisasacomplexinfection

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