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ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT
Rabbit papilloma virus seems uniquely to begin its proliferation in the nucleolus of infected cells. In cells near the germinal layer of the stratum Malpighii spherical viral bodies seem to develop within a reticulum which forms out of the fine granular matrix of the nucleolus. The virus may later f...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1959
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136998/ https://www.ncbi.nlm.nih.gov/pubmed/13834926 |
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author | Stone, Robert S. Shope, Richard E. Moore, Dan H. |
author_facet | Stone, Robert S. Shope, Richard E. Moore, Dan H. |
author_sort | Stone, Robert S. |
collection | PubMed |
description | Rabbit papilloma virus seems uniquely to begin its proliferation in the nucleolus of infected cells. In cells near the germinal layer of the stratum Malpighii spherical viral bodies seem to develop within a reticulum which forms out of the fine granular matrix of the nucleolus. The virus may later fill the nucleus and spread into the whole cell. The age of the cell, determined by its position in the Malpighian layer and by the extent of keratinization, can be correlated with the viral development. |
format | Text |
id | pubmed-2136998 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1959 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21369982008-04-17 ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT Stone, Robert S. Shope, Richard E. Moore, Dan H. J Exp Med Article Rabbit papilloma virus seems uniquely to begin its proliferation in the nucleolus of infected cells. In cells near the germinal layer of the stratum Malpighii spherical viral bodies seem to develop within a reticulum which forms out of the fine granular matrix of the nucleolus. The virus may later fill the nucleus and spread into the whole cell. The age of the cell, determined by its position in the Malpighian layer and by the extent of keratinization, can be correlated with the viral development. The Rockefeller University Press 1959-09-30 /pmc/articles/PMC2136998/ /pubmed/13834926 Text en Copyright © Copyright, 1959, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Stone, Robert S. Shope, Richard E. Moore, Dan H. ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT |
title | ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT |
title_full | ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT |
title_fullStr | ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT |
title_full_unstemmed | ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT |
title_short | ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT |
title_sort | electron microscope study of the development of the papilloma virus in the skin of the rabbit |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136998/ https://www.ncbi.nlm.nih.gov/pubmed/13834926 |
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