SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS : CYTOLOGICAL STUDIES AIDED BY FLUORESCEIN-LABELLED ANTIBODY

The sequential cytological changes which develop in tissue culture cells infected with adenovirus types 5 and 7 are described and compared with those produced by adenovirus types 1, 2, 3, and 4. The evidence that is presented indicates that types 1, 2, and 5 belong to one major subdivision of the ad...

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Detalles Bibliográficos
Autores principales: Boyer, Georgiana S., Denny, Floyd W., Ginsberg, Harold S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1959
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137019/
https://www.ncbi.nlm.nih.gov/pubmed/13803575
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author Boyer, Georgiana S.
Denny, Floyd W.
Ginsberg, Harold S.
author_facet Boyer, Georgiana S.
Denny, Floyd W.
Ginsberg, Harold S.
author_sort Boyer, Georgiana S.
collection PubMed
description The sequential cytological changes which develop in tissue culture cells infected with adenovirus types 5 and 7 are described and compared with those produced by adenovirus types 1, 2, 3, and 4. The evidence that is presented indicates that types 1, 2, and 5 belong to one major subdivision of the adenovirus group and types 3, 4, and 7 to another. That the host cell nucleus is the principal site of adenovirus synthesis has been confirmed by fluorescent antibody studies. They have demonstrated the occurrence of type-specific adenovirus antigen in the characteristic intranuclear inclusions and other virus-induced structures reported to contain virus-like particles or shown by electronmicroscopy.
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spelling pubmed-21370192008-04-17 SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS : CYTOLOGICAL STUDIES AIDED BY FLUORESCEIN-LABELLED ANTIBODY Boyer, Georgiana S. Denny, Floyd W. Ginsberg, Harold S. J Exp Med Article The sequential cytological changes which develop in tissue culture cells infected with adenovirus types 5 and 7 are described and compared with those produced by adenovirus types 1, 2, 3, and 4. The evidence that is presented indicates that types 1, 2, and 5 belong to one major subdivision of the adenovirus group and types 3, 4, and 7 to another. That the host cell nucleus is the principal site of adenovirus synthesis has been confirmed by fluorescent antibody studies. They have demonstrated the occurrence of type-specific adenovirus antigen in the characteristic intranuclear inclusions and other virus-induced structures reported to contain virus-like particles or shown by electronmicroscopy. The Rockefeller University Press 1959-10-31 /pmc/articles/PMC2137019/ /pubmed/13803575 Text en Copyright © Copyright, 1959, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Boyer, Georgiana S.
Denny, Floyd W.
Ginsberg, Harold S.
SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS : CYTOLOGICAL STUDIES AIDED BY FLUORESCEIN-LABELLED ANTIBODY
title SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS : CYTOLOGICAL STUDIES AIDED BY FLUORESCEIN-LABELLED ANTIBODY
title_full SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS : CYTOLOGICAL STUDIES AIDED BY FLUORESCEIN-LABELLED ANTIBODY
title_fullStr SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS : CYTOLOGICAL STUDIES AIDED BY FLUORESCEIN-LABELLED ANTIBODY
title_full_unstemmed SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS : CYTOLOGICAL STUDIES AIDED BY FLUORESCEIN-LABELLED ANTIBODY
title_short SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS : CYTOLOGICAL STUDIES AIDED BY FLUORESCEIN-LABELLED ANTIBODY
title_sort sequential cellular changes produced by types 5 and 7 adenoviruses in hela cells and in human amniotic cells : cytological studies aided by fluorescein-labelled antibody
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137019/
https://www.ncbi.nlm.nih.gov/pubmed/13803575
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AT dennyfloydw sequentialcellularchangesproducedbytypes5and7adenovirusesinhelacellsandinhumanamnioticcellscytologicalstudiesaidedbyfluoresceinlabelledantibody
AT ginsbergharolds sequentialcellularchangesproducedbytypes5and7adenovirusesinhelacellsandinhumanamnioticcellscytologicalstudiesaidedbyfluoresceinlabelledantibody

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