STUDIES ON THE ANTIGENIC PROPERTIES OF COMPLEMENT : I. DEMONSTRATION OF AGGLUTINATING ANTIBODIES AGAINST GUINEA PIG COMPLEMENT FIXED ON SENSITIZED SHEEP ERYTHROCYTES

Evidence is presented to show that guinea pig complement fixed on sensitized sheep red cells acts as a specific agglutinogen. Agglutinating antibodies that react with cell-fixed complement can be produced by immunizing rabbits with a complex of stromata-amboceptor-complement or with guinea pig serum...

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Detalles Bibliográficos
Autores principales: Klein, Paul G., Burkholder, Peter M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1960
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137196/
https://www.ncbi.nlm.nih.gov/pubmed/14409702
Descripción
Sumario:Evidence is presented to show that guinea pig complement fixed on sensitized sheep red cells acts as a specific agglutinogen. Agglutinating antibodies that react with cell-fixed complement can be produced by immunizing rabbits with a complex of stromata-amboceptor-complement or with guinea pig serum globulin. These agglutinins can be removed by precipitation with guinea pig serum. They are, therefore, distinct from immunoconglutinins.

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