ESTRADIOL REDUCES INCORPORATION OF RADIOACTIVE SULFATE INTO CARTILAGE AND AORTAS OF RATS

Estradiol in large amounts reduces the incorporation of radioactive sulfate into cartilage and aortas of rats. This reduction becomes apparent within 3 days for cartilage and 3 weeks for aorta. The effect is not mediated through suppression of testosterone secretion and the hypophysis is not necessa...

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Detalles Bibliográficos
Autores principales: Priest, Robert E., Koplitz, R. Marlene, Benditt, Earl P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1960
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137206/
https://www.ncbi.nlm.nih.gov/pubmed/13738006
Descripción
Sumario:Estradiol in large amounts reduces the incorporation of radioactive sulfate into cartilage and aortas of rats. This reduction becomes apparent within 3 days for cartilage and 3 weeks for aorta. The effect is not mediated through suppression of testosterone secretion and the hypophysis is not necessary for the effect to be demonstrated. The thoracic segment of aortas from normal rats incorporates more sulfate than does the abdominal segment and this difference is reduced following the administration of estradiol.

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