A CORRELATIVE STUDY BY ELECTRON AND LIGHT MICROSCOPY OF THE DEVELOPMENT OF TYPE 5 ADENOVIRUS : I. ELECTRON MICROSCOPY

Stages in the nuclear changes consequent to infection with type 5 adenovirus are shown and described. Viral development seems to be confined to the nucleus where characteristic particles are found. The shape of the intracellular virus depends upon the method of preservation employed, appearing spher...

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Detalles Bibliográficos
Autores principales: Morgan, Councilman, Godman, Gabriel C., Breitenfeld, Peter M., Rose, Harry M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1960
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137220/
https://www.ncbi.nlm.nih.gov/pubmed/13772565
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author Morgan, Councilman
Godman, Gabriel C.
Breitenfeld, Peter M.
Rose, Harry M.
author_facet Morgan, Councilman
Godman, Gabriel C.
Breitenfeld, Peter M.
Rose, Harry M.
author_sort Morgan, Councilman
collection PubMed
description Stages in the nuclear changes consequent to infection with type 5 adenovirus are shown and described. Viral development seems to be confined to the nucleus where characteristic particles are found. The shape of the intracellular virus depends upon the method of preservation employed, appearing spherical after osmium tetroxide or freezing-substitution, occasionally exhibiting angulated faces after formalin and often assuming an hexagonal profile after potassium permanganate. The non-viral crystals are encountered in zones of low density, and it is suggested that crystallization results from the accumulation of protein in these areas. An hypothesis is presented to explain why these crystals, in contrast to the insect polyhedra, contain few viral particles.
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spelling pubmed-21372202008-04-17 A CORRELATIVE STUDY BY ELECTRON AND LIGHT MICROSCOPY OF THE DEVELOPMENT OF TYPE 5 ADENOVIRUS : I. ELECTRON MICROSCOPY Morgan, Councilman Godman, Gabriel C. Breitenfeld, Peter M. Rose, Harry M. J Exp Med Article Stages in the nuclear changes consequent to infection with type 5 adenovirus are shown and described. Viral development seems to be confined to the nucleus where characteristic particles are found. The shape of the intracellular virus depends upon the method of preservation employed, appearing spherical after osmium tetroxide or freezing-substitution, occasionally exhibiting angulated faces after formalin and often assuming an hexagonal profile after potassium permanganate. The non-viral crystals are encountered in zones of low density, and it is suggested that crystallization results from the accumulation of protein in these areas. An hypothesis is presented to explain why these crystals, in contrast to the insect polyhedra, contain few viral particles. The Rockefeller University Press 1960-08-01 /pmc/articles/PMC2137220/ /pubmed/13772565 Text en Copyright © Copyright, 1960, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Morgan, Councilman
Godman, Gabriel C.
Breitenfeld, Peter M.
Rose, Harry M.
A CORRELATIVE STUDY BY ELECTRON AND LIGHT MICROSCOPY OF THE DEVELOPMENT OF TYPE 5 ADENOVIRUS : I. ELECTRON MICROSCOPY
title A CORRELATIVE STUDY BY ELECTRON AND LIGHT MICROSCOPY OF THE DEVELOPMENT OF TYPE 5 ADENOVIRUS : I. ELECTRON MICROSCOPY
title_full A CORRELATIVE STUDY BY ELECTRON AND LIGHT MICROSCOPY OF THE DEVELOPMENT OF TYPE 5 ADENOVIRUS : I. ELECTRON MICROSCOPY
title_fullStr A CORRELATIVE STUDY BY ELECTRON AND LIGHT MICROSCOPY OF THE DEVELOPMENT OF TYPE 5 ADENOVIRUS : I. ELECTRON MICROSCOPY
title_full_unstemmed A CORRELATIVE STUDY BY ELECTRON AND LIGHT MICROSCOPY OF THE DEVELOPMENT OF TYPE 5 ADENOVIRUS : I. ELECTRON MICROSCOPY
title_short A CORRELATIVE STUDY BY ELECTRON AND LIGHT MICROSCOPY OF THE DEVELOPMENT OF TYPE 5 ADENOVIRUS : I. ELECTRON MICROSCOPY
title_sort correlative study by electron and light microscopy of the development of type 5 adenovirus : i. electron microscopy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137220/
https://www.ncbi.nlm.nih.gov/pubmed/13772565
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