THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES : II. ACUTE GLOMERULONEPHRITIS IN RATS

The intravenous administration to rats of soluble antigen-antibody complexes in antigen excess resulted in acute glomerulonephritis. This occurred with both rabbit antiovalbumin and rabbit anti-BSA systems. The rats so treated regularly showed proteinuria and elevation of blood urea nitrogen. These...

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Detalles Bibliográficos
Autores principales: Benacerraf, Baruj, Potter, Jacobus L., McCluskey, Robert T., Miller, Frederick
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1960
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137255/
https://www.ncbi.nlm.nih.gov/pubmed/19867169
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author Benacerraf, Baruj
Potter, Jacobus L.
McCluskey, Robert T.
Miller, Frederick
author_facet Benacerraf, Baruj
Potter, Jacobus L.
McCluskey, Robert T.
Miller, Frederick
author_sort Benacerraf, Baruj
collection PubMed
description The intravenous administration to rats of soluble antigen-antibody complexes in antigen excess resulted in acute glomerulonephritis. This occurred with both rabbit antiovalbumin and rabbit anti-BSA systems. The rats so treated regularly showed proteinuria and elevation of blood urea nitrogen. These findings are compared with those reported in rats injected with anti-kidney serum.
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spelling pubmed-21372552008-04-17 THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES : II. ACUTE GLOMERULONEPHRITIS IN RATS Benacerraf, Baruj Potter, Jacobus L. McCluskey, Robert T. Miller, Frederick J Exp Med Article The intravenous administration to rats of soluble antigen-antibody complexes in antigen excess resulted in acute glomerulonephritis. This occurred with both rabbit antiovalbumin and rabbit anti-BSA systems. The rats so treated regularly showed proteinuria and elevation of blood urea nitrogen. These findings are compared with those reported in rats injected with anti-kidney serum. The Rockefeller University Press 1960-01-31 /pmc/articles/PMC2137255/ /pubmed/19867169 Text en ©Copyright 1960, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Benacerraf, Baruj
Potter, Jacobus L.
McCluskey, Robert T.
Miller, Frederick
THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES : II. ACUTE GLOMERULONEPHRITIS IN RATS
title THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES : II. ACUTE GLOMERULONEPHRITIS IN RATS
title_full THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES : II. ACUTE GLOMERULONEPHRITIS IN RATS
title_fullStr THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES : II. ACUTE GLOMERULONEPHRITIS IN RATS
title_full_unstemmed THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES : II. ACUTE GLOMERULONEPHRITIS IN RATS
title_short THE PATHOLOGIC EFFECTS OF INTRAVENOUSLY ADMINISTERED SOLUBLE ANTIGEN-ANTIBODY COMPLEXES : II. ACUTE GLOMERULONEPHRITIS IN RATS
title_sort pathologic effects of intravenously administered soluble antigen-antibody complexes : ii. acute glomerulonephritis in rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137255/
https://www.ncbi.nlm.nih.gov/pubmed/19867169
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