STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : III. MORPHOLOGICAL CHARACTERISTICS: INDEPENDENCE OF MORPHOLOGICAL AND FUNCTIONAL TRAITS

Seven strains of influenza A2 virus were serially passed in the chick embryo, and morphological characteristics of the passages were examined in the electron microscope. With serial passage there was a change from a prominently filamentous appearance in early passages to an almost entirely spherical...

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Detalles Bibliográficos
Autores principales: Choppin, Purnell W., Murphy, James S., Tamm, Igor
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1960
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137298/
https://www.ncbi.nlm.nih.gov/pubmed/13693270
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author Choppin, Purnell W.
Murphy, James S.
Tamm, Igor
author_facet Choppin, Purnell W.
Murphy, James S.
Tamm, Igor
author_sort Choppin, Purnell W.
collection PubMed
description Seven strains of influenza A2 virus were serially passed in the chick embryo, and morphological characteristics of the passages were examined in the electron microscope. With serial passage there was a change from a prominently filamentous appearance in early passages to an almost entirely spherical appearance in later passages. The number of passages required for the conversion to spherical morphology varied with different strains. The filament-sphere variation was found to be independent of the properties which differentiate "+" and "-" influenza A2 virus particles, and both highly filamentous and spherical populations of "+" and of "-" virus particles were obtained. The usefulness of these pairs of independent markers for genetic studies is discussed.
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spelling pubmed-21372982008-04-17 STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : III. MORPHOLOGICAL CHARACTERISTICS: INDEPENDENCE OF MORPHOLOGICAL AND FUNCTIONAL TRAITS Choppin, Purnell W. Murphy, James S. Tamm, Igor J Exp Med Article Seven strains of influenza A2 virus were serially passed in the chick embryo, and morphological characteristics of the passages were examined in the electron microscope. With serial passage there was a change from a prominently filamentous appearance in early passages to an almost entirely spherical appearance in later passages. The number of passages required for the conversion to spherical morphology varied with different strains. The filament-sphere variation was found to be independent of the properties which differentiate "+" and "-" influenza A2 virus particles, and both highly filamentous and spherical populations of "+" and of "-" virus particles were obtained. The usefulness of these pairs of independent markers for genetic studies is discussed. The Rockefeller University Press 1960-10-31 /pmc/articles/PMC2137298/ /pubmed/13693270 Text en Copyright © Copyright, 1960, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Choppin, Purnell W.
Murphy, James S.
Tamm, Igor
STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : III. MORPHOLOGICAL CHARACTERISTICS: INDEPENDENCE OF MORPHOLOGICAL AND FUNCTIONAL TRAITS
title STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : III. MORPHOLOGICAL CHARACTERISTICS: INDEPENDENCE OF MORPHOLOGICAL AND FUNCTIONAL TRAITS
title_full STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : III. MORPHOLOGICAL CHARACTERISTICS: INDEPENDENCE OF MORPHOLOGICAL AND FUNCTIONAL TRAITS
title_fullStr STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : III. MORPHOLOGICAL CHARACTERISTICS: INDEPENDENCE OF MORPHOLOGICAL AND FUNCTIONAL TRAITS
title_full_unstemmed STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : III. MORPHOLOGICAL CHARACTERISTICS: INDEPENDENCE OF MORPHOLOGICAL AND FUNCTIONAL TRAITS
title_short STUDIES OF TWO KINDS OF VIRUS PARTICLES WHICH COMPRISE INFLUENZA A2 VIRUS STRAINS : III. MORPHOLOGICAL CHARACTERISTICS: INDEPENDENCE OF MORPHOLOGICAL AND FUNCTIONAL TRAITS
title_sort studies of two kinds of virus particles which comprise influenza a2 virus strains : iii. morphological characteristics: independence of morphological and functional traits
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137298/
https://www.ncbi.nlm.nih.gov/pubmed/13693270
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