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THE LEVEL OF LACTIC DEHYDROGENASE ACTIVITY AS AN INDICATOR OF THE GROWTH OF INFLUENZA VIRUS IN THE EMBRYONATE EGG
The relation, between time and the levels of lactic dehydrogenase activity of chorioallantoic fluids from embryonate eggs infected with the PR8 strain of influenza virus were determined quantitatively. The mean values, based on 10 determinations for each time interval, followed a sigmoid curve, with...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1961
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137339/ https://www.ncbi.nlm.nih.gov/pubmed/13752398 |
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author | Kelly, Richard Greiff, Donald |
author_facet | Kelly, Richard Greiff, Donald |
author_sort | Kelly, Richard |
collection | PubMed |
description | The relation, between time and the levels of lactic dehydrogenase activity of chorioallantoic fluids from embryonate eggs infected with the PR8 strain of influenza virus were determined quantitatively. The mean values, based on 10 determinations for each time interval, followed a sigmoid curve, with the greatest rates of change occurring between 48 and 72 hours after the inoculation of virus. The activities of the fluids from infected eggs at the 72nd hour or later were approximately 18 times higher than those from non-infected eggs. Based on the data above, a qualitative test for the presence of infection with influenza virus was developed. |
format | Text |
id | pubmed-2137339 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1961 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21373392008-04-17 THE LEVEL OF LACTIC DEHYDROGENASE ACTIVITY AS AN INDICATOR OF THE GROWTH OF INFLUENZA VIRUS IN THE EMBRYONATE EGG Kelly, Richard Greiff, Donald J Exp Med Article The relation, between time and the levels of lactic dehydrogenase activity of chorioallantoic fluids from embryonate eggs infected with the PR8 strain of influenza virus were determined quantitatively. The mean values, based on 10 determinations for each time interval, followed a sigmoid curve, with the greatest rates of change occurring between 48 and 72 hours after the inoculation of virus. The activities of the fluids from infected eggs at the 72nd hour or later were approximately 18 times higher than those from non-infected eggs. Based on the data above, a qualitative test for the presence of infection with influenza virus was developed. The Rockefeller University Press 1961-01-01 /pmc/articles/PMC2137339/ /pubmed/13752398 Text en Copyright © Copyright, 1961, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Kelly, Richard Greiff, Donald THE LEVEL OF LACTIC DEHYDROGENASE ACTIVITY AS AN INDICATOR OF THE GROWTH OF INFLUENZA VIRUS IN THE EMBRYONATE EGG |
title | THE LEVEL OF LACTIC DEHYDROGENASE ACTIVITY AS AN INDICATOR OF THE GROWTH OF INFLUENZA VIRUS IN THE EMBRYONATE EGG |
title_full | THE LEVEL OF LACTIC DEHYDROGENASE ACTIVITY AS AN INDICATOR OF THE GROWTH OF INFLUENZA VIRUS IN THE EMBRYONATE EGG |
title_fullStr | THE LEVEL OF LACTIC DEHYDROGENASE ACTIVITY AS AN INDICATOR OF THE GROWTH OF INFLUENZA VIRUS IN THE EMBRYONATE EGG |
title_full_unstemmed | THE LEVEL OF LACTIC DEHYDROGENASE ACTIVITY AS AN INDICATOR OF THE GROWTH OF INFLUENZA VIRUS IN THE EMBRYONATE EGG |
title_short | THE LEVEL OF LACTIC DEHYDROGENASE ACTIVITY AS AN INDICATOR OF THE GROWTH OF INFLUENZA VIRUS IN THE EMBRYONATE EGG |
title_sort | level of lactic dehydrogenase activity as an indicator of the growth of influenza virus in the embryonate egg |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137339/ https://www.ncbi.nlm.nih.gov/pubmed/13752398 |
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