ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE

In rats thymectomized at birth and tested in adult life, ability to develop autoallergic encephalomyelitis was completely suppressed, there was a marked diminution in the degree of tuberculin sensitization appearing after a single injection of mycobacteria in oil, rejection of skin homografts was ma...

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Detalles Bibliográficos
Autores principales: Arnason, Barry G., Janković, Branislav D., Waksman, Byron H., Wennersten, Christine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1962
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137389/
https://www.ncbi.nlm.nih.gov/pubmed/13862386
Descripción
Sumario:In rats thymectomized at birth and tested in adult life, ability to develop autoallergic encephalomyelitis was completely suppressed, there was a marked diminution in the degree of tuberculin sensitization appearing after a single injection of mycobacteria in oil, rejection of skin homografts was markedly delayed, and adjuvant arthritis was not appreciably affected. At the same time there was a striking decrease in the circulating level of small lymphocytes.

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