Cargando…
ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE
In rats thymectomized at birth and tested in adult life, ability to develop autoallergic encephalomyelitis was completely suppressed, there was a marked diminution in the degree of tuberculin sensitization appearing after a single injection of mycobacteria in oil, rejection of skin homografts was ma...
Autores principales: | , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1962
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137389/ https://www.ncbi.nlm.nih.gov/pubmed/13862386 |
_version_ | 1782143320325095424 |
---|---|
author | Arnason, Barry G. Janković, Branislav D. Waksman, Byron H. Wennersten, Christine |
author_facet | Arnason, Barry G. Janković, Branislav D. Waksman, Byron H. Wennersten, Christine |
author_sort | Arnason, Barry G. |
collection | PubMed |
description | In rats thymectomized at birth and tested in adult life, ability to develop autoallergic encephalomyelitis was completely suppressed, there was a marked diminution in the degree of tuberculin sensitization appearing after a single injection of mycobacteria in oil, rejection of skin homografts was markedly delayed, and adjuvant arthritis was not appreciably affected. At the same time there was a striking decrease in the circulating level of small lymphocytes. |
format | Text |
id | pubmed-2137389 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1962 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21373892008-04-17 ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE Arnason, Barry G. Janković, Branislav D. Waksman, Byron H. Wennersten, Christine J Exp Med Article In rats thymectomized at birth and tested in adult life, ability to develop autoallergic encephalomyelitis was completely suppressed, there was a marked diminution in the degree of tuberculin sensitization appearing after a single injection of mycobacteria in oil, rejection of skin homografts was markedly delayed, and adjuvant arthritis was not appreciably affected. At the same time there was a striking decrease in the circulating level of small lymphocytes. The Rockefeller University Press 1962-08-01 /pmc/articles/PMC2137389/ /pubmed/13862386 Text en Copyright © Copyright, 1962, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Arnason, Barry G. Janković, Branislav D. Waksman, Byron H. Wennersten, Christine ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE |
title | ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE |
title_full | ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE |
title_fullStr | ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE |
title_full_unstemmed | ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE |
title_short | ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS : II. SUPPRESSIVE EFFECT OF THYMECTOMY AT BIRTH ON REACTIONS OF DELAYED (CELLULAR) HYPERSENSITIVITY AND THE CIRCULATING SMALL LYMPHOCYTE |
title_sort | role of the thymus in immune reactions in rats : ii. suppressive effect of thymectomy at birth on reactions of delayed (cellular) hypersensitivity and the circulating small lymphocyte |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137389/ https://www.ncbi.nlm.nih.gov/pubmed/13862386 |
work_keys_str_mv | AT arnasonbarryg roleofthethymusinimmunereactionsinratsiisuppressiveeffectofthymectomyatbirthonreactionsofdelayedcellularhypersensitivityandthecirculatingsmalllymphocyte AT jankovicbranislavd roleofthethymusinimmunereactionsinratsiisuppressiveeffectofthymectomyatbirthonreactionsofdelayedcellularhypersensitivityandthecirculatingsmalllymphocyte AT waksmanbyronh roleofthethymusinimmunereactionsinratsiisuppressiveeffectofthymectomyatbirthonreactionsofdelayedcellularhypersensitivityandthecirculatingsmalllymphocyte AT wennerstenchristine roleofthethymusinimmunereactionsinratsiisuppressiveeffectofthymectomyatbirthonreactionsofdelayedcellularhypersensitivityandthecirculatingsmalllymphocyte |