Cargando…

EFFECTS OF CHRONIC EXCESS SALT INGESTION : EVIDENCE THAT GENETIC FACTORS PLAY AN IMPORTANT ROLE IN SUSCEPTIBILITY TO EXPERIMENTAL HYPERTENSION

Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a hig...

Descripción completa

Detalles Bibliográficos
Autores principales: Dahl, Lewis K., Heine, Martha, Tassinari, Lorraine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1962
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137393/
https://www.ncbi.nlm.nih.gov/pubmed/13883089
_version_ 1782143321286639616
author Dahl, Lewis K.
Heine, Martha
Tassinari, Lorraine
author_facet Dahl, Lewis K.
Heine, Martha
Tassinari, Lorraine
author_sort Dahl, Lewis K.
collection PubMed
description Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet. It was suggested that similar genetic factors operate in man.
format Text
id pubmed-2137393
institution National Center for Biotechnology Information
language English
publishDate 1962
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21373932008-04-17 EFFECTS OF CHRONIC EXCESS SALT INGESTION : EVIDENCE THAT GENETIC FACTORS PLAY AN IMPORTANT ROLE IN SUSCEPTIBILITY TO EXPERIMENTAL HYPERTENSION Dahl, Lewis K. Heine, Martha Tassinari, Lorraine J Exp Med Article Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet. It was suggested that similar genetic factors operate in man. The Rockefeller University Press 1962-06-01 /pmc/articles/PMC2137393/ /pubmed/13883089 Text en Copyright © Copyright, 1962, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dahl, Lewis K.
Heine, Martha
Tassinari, Lorraine
EFFECTS OF CHRONIC EXCESS SALT INGESTION : EVIDENCE THAT GENETIC FACTORS PLAY AN IMPORTANT ROLE IN SUSCEPTIBILITY TO EXPERIMENTAL HYPERTENSION
title EFFECTS OF CHRONIC EXCESS SALT INGESTION : EVIDENCE THAT GENETIC FACTORS PLAY AN IMPORTANT ROLE IN SUSCEPTIBILITY TO EXPERIMENTAL HYPERTENSION
title_full EFFECTS OF CHRONIC EXCESS SALT INGESTION : EVIDENCE THAT GENETIC FACTORS PLAY AN IMPORTANT ROLE IN SUSCEPTIBILITY TO EXPERIMENTAL HYPERTENSION
title_fullStr EFFECTS OF CHRONIC EXCESS SALT INGESTION : EVIDENCE THAT GENETIC FACTORS PLAY AN IMPORTANT ROLE IN SUSCEPTIBILITY TO EXPERIMENTAL HYPERTENSION
title_full_unstemmed EFFECTS OF CHRONIC EXCESS SALT INGESTION : EVIDENCE THAT GENETIC FACTORS PLAY AN IMPORTANT ROLE IN SUSCEPTIBILITY TO EXPERIMENTAL HYPERTENSION
title_short EFFECTS OF CHRONIC EXCESS SALT INGESTION : EVIDENCE THAT GENETIC FACTORS PLAY AN IMPORTANT ROLE IN SUSCEPTIBILITY TO EXPERIMENTAL HYPERTENSION
title_sort effects of chronic excess salt ingestion : evidence that genetic factors play an important role in susceptibility to experimental hypertension
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137393/
https://www.ncbi.nlm.nih.gov/pubmed/13883089
work_keys_str_mv AT dahllewisk effectsofchronicexcesssaltingestionevidencethatgeneticfactorsplayanimportantroleinsusceptibilitytoexperimentalhypertension
AT heinemartha effectsofchronicexcesssaltingestionevidencethatgeneticfactorsplayanimportantroleinsusceptibilitytoexperimentalhypertension
AT tassinarilorraine effectsofchronicexcesssaltingestionevidencethatgeneticfactorsplayanimportantroleinsusceptibilitytoexperimentalhypertension