THE ANALYSIS OF STREPTOCOCCAL INFECTIONS : VI. IMMUNOELECTROPHORETIC OBSERVATIONS ON EXTRACELLULAR ANTIGENS DETECTABLE WITH: HUMAN ANTIBODIES

It has been found by immunoelectrophoresis, that Group A streptococci release at least 20 distinct extracellular antigens in human tissues, as judged by naturally occurring antibodies present in normal pooled human gamma globulin. Several of these precipitin arcs have been identified with streptococ...

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Detalles Bibliográficos
Autores principales: Halbert, Seymour P., Keatinge, Suzanne L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1961
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137428/
https://www.ncbi.nlm.nih.gov/pubmed/13710682
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author Halbert, Seymour P.
Keatinge, Suzanne L.
author_facet Halbert, Seymour P.
Keatinge, Suzanne L.
author_sort Halbert, Seymour P.
collection PubMed
description It has been found by immunoelectrophoresis, that Group A streptococci release at least 20 distinct extracellular antigens in human tissues, as judged by naturally occurring antibodies present in normal pooled human gamma globulin. Several of these precipitin arcs have been identified with streptococcal antigens previously purified by electrophoresis and chromatography. Human gamma globulin, as well as several rheumatic fever sera, were shown to be remarkably potent in antistreptococcal antibodies, when compared to four horse antibody concentrates obtained by hyperimmunization with several streptococcal filtrates. A Group C streptococcal culture concentrate revealed 8 or 9 antigens for which corresponding antibodies were present in human gamma globulin.
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spelling pubmed-21374282008-04-17 THE ANALYSIS OF STREPTOCOCCAL INFECTIONS : VI. IMMUNOELECTROPHORETIC OBSERVATIONS ON EXTRACELLULAR ANTIGENS DETECTABLE WITH: HUMAN ANTIBODIES Halbert, Seymour P. Keatinge, Suzanne L. J Exp Med Article It has been found by immunoelectrophoresis, that Group A streptococci release at least 20 distinct extracellular antigens in human tissues, as judged by naturally occurring antibodies present in normal pooled human gamma globulin. Several of these precipitin arcs have been identified with streptococcal antigens previously purified by electrophoresis and chromatography. Human gamma globulin, as well as several rheumatic fever sera, were shown to be remarkably potent in antistreptococcal antibodies, when compared to four horse antibody concentrates obtained by hyperimmunization with several streptococcal filtrates. A Group C streptococcal culture concentrate revealed 8 or 9 antigens for which corresponding antibodies were present in human gamma globulin. The Rockefeller University Press 1961-06-01 /pmc/articles/PMC2137428/ /pubmed/13710682 Text en Copyright © Copyright, 1961, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Halbert, Seymour P.
Keatinge, Suzanne L.
THE ANALYSIS OF STREPTOCOCCAL INFECTIONS : VI. IMMUNOELECTROPHORETIC OBSERVATIONS ON EXTRACELLULAR ANTIGENS DETECTABLE WITH: HUMAN ANTIBODIES
title THE ANALYSIS OF STREPTOCOCCAL INFECTIONS : VI. IMMUNOELECTROPHORETIC OBSERVATIONS ON EXTRACELLULAR ANTIGENS DETECTABLE WITH: HUMAN ANTIBODIES
title_full THE ANALYSIS OF STREPTOCOCCAL INFECTIONS : VI. IMMUNOELECTROPHORETIC OBSERVATIONS ON EXTRACELLULAR ANTIGENS DETECTABLE WITH: HUMAN ANTIBODIES
title_fullStr THE ANALYSIS OF STREPTOCOCCAL INFECTIONS : VI. IMMUNOELECTROPHORETIC OBSERVATIONS ON EXTRACELLULAR ANTIGENS DETECTABLE WITH: HUMAN ANTIBODIES
title_full_unstemmed THE ANALYSIS OF STREPTOCOCCAL INFECTIONS : VI. IMMUNOELECTROPHORETIC OBSERVATIONS ON EXTRACELLULAR ANTIGENS DETECTABLE WITH: HUMAN ANTIBODIES
title_short THE ANALYSIS OF STREPTOCOCCAL INFECTIONS : VI. IMMUNOELECTROPHORETIC OBSERVATIONS ON EXTRACELLULAR ANTIGENS DETECTABLE WITH: HUMAN ANTIBODIES
title_sort analysis of streptococcal infections : vi. immunoelectrophoretic observations on extracellular antigens detectable with: human antibodies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137428/
https://www.ncbi.nlm.nih.gov/pubmed/13710682
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