THE CHANGES IN SERUM PROTEINS AND BLOOD VOLUME DURING IMMUNIZATION

In rabbits hyperimmunized with pneumococcal vaccine high concentrations of gamma globulin are produced. In such rabbits, plasma volume was determined with (131)I-labelled rabbit albumin and red cell volume with (51)-Cr-labelled autologous red cells. It was found that the plasma volume increased with...

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Detalles Bibliográficos
Autores principales: Bjørneboe, M., Jarnum, Stig
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1961
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137431/
https://www.ncbi.nlm.nih.gov/pubmed/19867190
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author Bjørneboe, M.
Jarnum, Stig
author_facet Bjørneboe, M.
Jarnum, Stig
author_sort Bjørneboe, M.
collection PubMed
description In rabbits hyperimmunized with pneumococcal vaccine high concentrations of gamma globulin are produced. In such rabbits, plasma volume was determined with (131)I-labelled rabbit albumin and red cell volume with (51)-Cr-labelled autologous red cells. It was found that the plasma volume increased with increasing gamma globulin concentration, the highest values observed being about 10 gm. per cent gamma globulin and about 70 ml. plasma per kg as against normal values of 0.6 to 0.7 gm. per cent gamma globulin and 30 ml. plasma per kg. The red cell volume was the same in immunized and in normal rabbits and consequently hemoglobin concentration fell with increasing gamma globulin.
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spelling pubmed-21374312008-04-17 THE CHANGES IN SERUM PROTEINS AND BLOOD VOLUME DURING IMMUNIZATION Bjørneboe, M. Jarnum, Stig J Exp Med Article In rabbits hyperimmunized with pneumococcal vaccine high concentrations of gamma globulin are produced. In such rabbits, plasma volume was determined with (131)I-labelled rabbit albumin and red cell volume with (51)-Cr-labelled autologous red cells. It was found that the plasma volume increased with increasing gamma globulin concentration, the highest values observed being about 10 gm. per cent gamma globulin and about 70 ml. plasma per kg as against normal values of 0.6 to 0.7 gm. per cent gamma globulin and 30 ml. plasma per kg. The red cell volume was the same in immunized and in normal rabbits and consequently hemoglobin concentration fell with increasing gamma globulin. The Rockefeller University Press 1961-06-01 /pmc/articles/PMC2137431/ /pubmed/19867190 Text en Copyright © Copyright, 1961, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Bjørneboe, M.
Jarnum, Stig
THE CHANGES IN SERUM PROTEINS AND BLOOD VOLUME DURING IMMUNIZATION
title THE CHANGES IN SERUM PROTEINS AND BLOOD VOLUME DURING IMMUNIZATION
title_full THE CHANGES IN SERUM PROTEINS AND BLOOD VOLUME DURING IMMUNIZATION
title_fullStr THE CHANGES IN SERUM PROTEINS AND BLOOD VOLUME DURING IMMUNIZATION
title_full_unstemmed THE CHANGES IN SERUM PROTEINS AND BLOOD VOLUME DURING IMMUNIZATION
title_short THE CHANGES IN SERUM PROTEINS AND BLOOD VOLUME DURING IMMUNIZATION
title_sort changes in serum proteins and blood volume during immunization
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137431/
https://www.ncbi.nlm.nih.gov/pubmed/19867190
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