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EXPERIMENTAL GENETIC RECOMBINATION IN VIVO BETWEEN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM
Antibiotic-pretreated mice were fed orally an Hfr culture of streptomycin-resistant E. coli and 1 day later, a streptomycin-resistant F(-) S. typhimurium culture. Hybrids were recovered in relatively small numbers from the feces of these mice within 24 hours demonstrating that genetic recombination...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1961
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137439/ https://www.ncbi.nlm.nih.gov/pubmed/13748213 |
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author | Schneider, H. Formal, Samuel B. Baron, L. S. |
author_facet | Schneider, H. Formal, Samuel B. Baron, L. S. |
author_sort | Schneider, H. |
collection | PubMed |
description | Antibiotic-pretreated mice were fed orally an Hfr culture of streptomycin-resistant E. coli and 1 day later, a streptomycin-resistant F(-) S. typhimurium culture. Hybrids were recovered in relatively small numbers from the feces of these mice within 24 hours demonstrating that genetic recombination can occur within the intestinal tract of a mammalian host under experimental conditions. These hybrids multiplied rapidly and persisted throughout the course of the experiment. In addition, hybrids were recovered which had not been observed in single matings performed in vitro. |
format | Text |
id | pubmed-2137439 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1961 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21374392008-04-17 EXPERIMENTAL GENETIC RECOMBINATION IN VIVO BETWEEN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM Schneider, H. Formal, Samuel B. Baron, L. S. J Exp Med Article Antibiotic-pretreated mice were fed orally an Hfr culture of streptomycin-resistant E. coli and 1 day later, a streptomycin-resistant F(-) S. typhimurium culture. Hybrids were recovered in relatively small numbers from the feces of these mice within 24 hours demonstrating that genetic recombination can occur within the intestinal tract of a mammalian host under experimental conditions. These hybrids multiplied rapidly and persisted throughout the course of the experiment. In addition, hybrids were recovered which had not been observed in single matings performed in vitro. The Rockefeller University Press 1961-07-01 /pmc/articles/PMC2137439/ /pubmed/13748213 Text en Copyright © Copyright, 1961, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Schneider, H. Formal, Samuel B. Baron, L. S. EXPERIMENTAL GENETIC RECOMBINATION IN VIVO BETWEEN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM |
title | EXPERIMENTAL GENETIC RECOMBINATION IN VIVO BETWEEN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM |
title_full | EXPERIMENTAL GENETIC RECOMBINATION IN VIVO BETWEEN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM |
title_fullStr | EXPERIMENTAL GENETIC RECOMBINATION IN VIVO BETWEEN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM |
title_full_unstemmed | EXPERIMENTAL GENETIC RECOMBINATION IN VIVO BETWEEN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM |
title_short | EXPERIMENTAL GENETIC RECOMBINATION IN VIVO BETWEEN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM |
title_sort | experimental genetic recombination in vivo between escherichia coli and salmonella typhimurium |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137439/ https://www.ncbi.nlm.nih.gov/pubmed/13748213 |
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