STUDIES ON INFECTION AND IMMUNITY IN EXPERIMENTAL TYPHOID FEVER : III. EFFECT OF PROPHYLACTIC IMMUNIZATION

A study was made of the efficacy of various antityphoid immunizing agents in immunizing chimpanzees against typhoid fever produced by feeding viable S. typhosa. It was found that both acetone-killed and heat-killed, phenol-preserved typhoid vaccines were effective in protecting against infection ind...

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Detalles Bibliográficos
Autores principales: Gaines, Sidney, Landy, Maurice, Edsall, Geoffrey, Mandel, Adrian D., Trapani, R.-J., Benenson, A. S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1961
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137464/
https://www.ncbi.nlm.nih.gov/pubmed/13702952
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author Gaines, Sidney
Landy, Maurice
Edsall, Geoffrey
Mandel, Adrian D.
Trapani, R.-J.
Benenson, A. S.
author_facet Gaines, Sidney
Landy, Maurice
Edsall, Geoffrey
Mandel, Adrian D.
Trapani, R.-J.
Benenson, A. S.
author_sort Gaines, Sidney
collection PubMed
description A study was made of the efficacy of various antityphoid immunizing agents in immunizing chimpanzees against typhoid fever produced by feeding viable S. typhosa. It was found that both acetone-killed and heat-killed, phenol-preserved typhoid vaccines were effective in protecting against infection induced with either homologous or heterologous strains of typhoid bacilli. Purified O antigen induced no discernible protection, but some immunity was afforded by the administration of purified Vi antigen.
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spelling pubmed-21374642008-04-17 STUDIES ON INFECTION AND IMMUNITY IN EXPERIMENTAL TYPHOID FEVER : III. EFFECT OF PROPHYLACTIC IMMUNIZATION Gaines, Sidney Landy, Maurice Edsall, Geoffrey Mandel, Adrian D. Trapani, R.-J. Benenson, A. S. J Exp Med Article A study was made of the efficacy of various antityphoid immunizing agents in immunizing chimpanzees against typhoid fever produced by feeding viable S. typhosa. It was found that both acetone-killed and heat-killed, phenol-preserved typhoid vaccines were effective in protecting against infection induced with either homologous or heterologous strains of typhoid bacilli. Purified O antigen induced no discernible protection, but some immunity was afforded by the administration of purified Vi antigen. The Rockefeller University Press 1961-09-01 /pmc/articles/PMC2137464/ /pubmed/13702952 Text en Copyright © Copyright, 1961, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Gaines, Sidney
Landy, Maurice
Edsall, Geoffrey
Mandel, Adrian D.
Trapani, R.-J.
Benenson, A. S.
STUDIES ON INFECTION AND IMMUNITY IN EXPERIMENTAL TYPHOID FEVER : III. EFFECT OF PROPHYLACTIC IMMUNIZATION
title STUDIES ON INFECTION AND IMMUNITY IN EXPERIMENTAL TYPHOID FEVER : III. EFFECT OF PROPHYLACTIC IMMUNIZATION
title_full STUDIES ON INFECTION AND IMMUNITY IN EXPERIMENTAL TYPHOID FEVER : III. EFFECT OF PROPHYLACTIC IMMUNIZATION
title_fullStr STUDIES ON INFECTION AND IMMUNITY IN EXPERIMENTAL TYPHOID FEVER : III. EFFECT OF PROPHYLACTIC IMMUNIZATION
title_full_unstemmed STUDIES ON INFECTION AND IMMUNITY IN EXPERIMENTAL TYPHOID FEVER : III. EFFECT OF PROPHYLACTIC IMMUNIZATION
title_short STUDIES ON INFECTION AND IMMUNITY IN EXPERIMENTAL TYPHOID FEVER : III. EFFECT OF PROPHYLACTIC IMMUNIZATION
title_sort studies on infection and immunity in experimental typhoid fever : iii. effect of prophylactic immunization
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137464/
https://www.ncbi.nlm.nih.gov/pubmed/13702952
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