THE FATE OF INJECTED BENCE JONES PROTEIN

Bence Jones protein injected into rabbits was excreted rapidly into the urine. The excreted protein retained the physicochemical and immunochemical properties of the injected Bence Jones protein. In spite of the rapid excretion, a significant portion of the injected Bence Jones protein was found to...

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Detalles Bibliográficos
Autores principales: Meyer, Franz, Putnam, Frank W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1963
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137613/
https://www.ncbi.nlm.nih.gov/pubmed/13935269
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author Meyer, Franz
Putnam, Frank W.
author_facet Meyer, Franz
Putnam, Frank W.
author_sort Meyer, Franz
collection PubMed
description Bence Jones protein injected into rabbits was excreted rapidly into the urine. The excreted protein retained the physicochemical and immunochemical properties of the injected Bence Jones protein. In spite of the rapid excretion, a significant portion of the injected Bence Jones protein was found to be metabolized. After reinjection of radioactive Bence Jones protein into the donor patient, only a little radioactivity was recovered in the urinary protein. The implications of these results are discussed.
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spelling pubmed-21376132008-04-17 THE FATE OF INJECTED BENCE JONES PROTEIN Meyer, Franz Putnam, Frank W. J Exp Med Article Bence Jones protein injected into rabbits was excreted rapidly into the urine. The excreted protein retained the physicochemical and immunochemical properties of the injected Bence Jones protein. In spite of the rapid excretion, a significant portion of the injected Bence Jones protein was found to be metabolized. After reinjection of radioactive Bence Jones protein into the donor patient, only a little radioactivity was recovered in the urinary protein. The implications of these results are discussed. The Rockefeller University Press 1963-03-31 /pmc/articles/PMC2137613/ /pubmed/13935269 Text en Copyright ©, 1963, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Meyer, Franz
Putnam, Frank W.
THE FATE OF INJECTED BENCE JONES PROTEIN
title THE FATE OF INJECTED BENCE JONES PROTEIN
title_full THE FATE OF INJECTED BENCE JONES PROTEIN
title_fullStr THE FATE OF INJECTED BENCE JONES PROTEIN
title_full_unstemmed THE FATE OF INJECTED BENCE JONES PROTEIN
title_short THE FATE OF INJECTED BENCE JONES PROTEIN
title_sort fate of injected bence jones protein
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137613/
https://www.ncbi.nlm.nih.gov/pubmed/13935269
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