STUDIES ON THE MECHANISM OF THE LONG CHAIN PHENOMENON OF GROUP A STREPTOCOCCI

The formation and destruction of long chains by growth of Group A streptococci in the presence of type-specific antibody have been studied with the fluorescent antibody technique. Long chain formation has been shown to depend on the presence of free antibody during the growth of the bacteria. Destru...

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Autores principales: Hahn, Jerome J., Cole, Roger M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1963
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137616/
https://www.ncbi.nlm.nih.gov/pubmed/13951944
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author Hahn, Jerome J.
Cole, Roger M.
author_facet Hahn, Jerome J.
Cole, Roger M.
author_sort Hahn, Jerome J.
collection PubMed
description The formation and destruction of long chains by growth of Group A streptococci in the presence of type-specific antibody have been studied with the fluorescent antibody technique. Long chain formation has been shown to depend on the presence of free antibody during the growth of the bacteria. Destruction of long chains has been shown to depend on the continued growth and division of the bacteria in the absence of free antibody. Univalent antibody fragments formed by proteolytic digestion of antibody globulin have been shown to have the combining properties of untreated antibody but do not result in the production of long chains. A model involving end-to-end agglutination during growth of Group A streptococci has been presented to explain the mechanism of production of long chains by growth of Group A streptococci in the presence of type-specific antibody.
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spelling pubmed-21376162008-04-17 STUDIES ON THE MECHANISM OF THE LONG CHAIN PHENOMENON OF GROUP A STREPTOCOCCI Hahn, Jerome J. Cole, Roger M. J Exp Med Article The formation and destruction of long chains by growth of Group A streptococci in the presence of type-specific antibody have been studied with the fluorescent antibody technique. Long chain formation has been shown to depend on the presence of free antibody during the growth of the bacteria. Destruction of long chains has been shown to depend on the continued growth and division of the bacteria in the absence of free antibody. Univalent antibody fragments formed by proteolytic digestion of antibody globulin have been shown to have the combining properties of untreated antibody but do not result in the production of long chains. A model involving end-to-end agglutination during growth of Group A streptococci has been presented to explain the mechanism of production of long chains by growth of Group A streptococci in the presence of type-specific antibody. The Rockefeller University Press 1963-03-31 /pmc/articles/PMC2137616/ /pubmed/13951944 Text en Copyright ©, 1963, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hahn, Jerome J.
Cole, Roger M.
STUDIES ON THE MECHANISM OF THE LONG CHAIN PHENOMENON OF GROUP A STREPTOCOCCI
title STUDIES ON THE MECHANISM OF THE LONG CHAIN PHENOMENON OF GROUP A STREPTOCOCCI
title_full STUDIES ON THE MECHANISM OF THE LONG CHAIN PHENOMENON OF GROUP A STREPTOCOCCI
title_fullStr STUDIES ON THE MECHANISM OF THE LONG CHAIN PHENOMENON OF GROUP A STREPTOCOCCI
title_full_unstemmed STUDIES ON THE MECHANISM OF THE LONG CHAIN PHENOMENON OF GROUP A STREPTOCOCCI
title_short STUDIES ON THE MECHANISM OF THE LONG CHAIN PHENOMENON OF GROUP A STREPTOCOCCI
title_sort studies on the mechanism of the long chain phenomenon of group a streptococci
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137616/
https://www.ncbi.nlm.nih.gov/pubmed/13951944
work_keys_str_mv AT hahnjeromej studiesonthemechanismofthelongchainphenomenonofgroupastreptococci
AT colerogerm studiesonthemechanismofthelongchainphenomenonofgroupastreptococci

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