REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN

Injection into rabbits of a consistently lethal dose of endotoxin regularly produced a rapid and sustained fall of complement levels and lowered the titers of antibody to endotoxin. Doses of endotoxin below the LD(50) lowered complement levels sporadically but not the titers of antibody to endotoxin...

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Detalles Bibliográficos
Autores principales: Gilbert, Verne E., Braude, Abraham I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1962
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137625/
https://www.ncbi.nlm.nih.gov/pubmed/13947829
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author Gilbert, Verne E.
Braude, Abraham I.
author_facet Gilbert, Verne E.
Braude, Abraham I.
author_sort Gilbert, Verne E.
collection PubMed
description Injection into rabbits of a consistently lethal dose of endotoxin regularly produced a rapid and sustained fall of complement levels and lowered the titers of antibody to endotoxin. Doses of endotoxin below the LD(50) lowered complement levels sporadically but not the titers of antibody to endotoxin. The possibility is discussed that complement may be involved in the mechanisms responsible for the lethal action of endotoxin.
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spelling pubmed-21376252008-04-17 REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN Gilbert, Verne E. Braude, Abraham I. J Exp Med Article Injection into rabbits of a consistently lethal dose of endotoxin regularly produced a rapid and sustained fall of complement levels and lowered the titers of antibody to endotoxin. Doses of endotoxin below the LD(50) lowered complement levels sporadically but not the titers of antibody to endotoxin. The possibility is discussed that complement may be involved in the mechanisms responsible for the lethal action of endotoxin. The Rockefeller University Press 1962-10-01 /pmc/articles/PMC2137625/ /pubmed/13947829 Text en ©Copyright, 1962, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Gilbert, Verne E.
Braude, Abraham I.
REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN
title REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN
title_full REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN
title_fullStr REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN
title_full_unstemmed REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN
title_short REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN
title_sort reduction of serum complement in rabbits after injection of endotoxin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137625/
https://www.ncbi.nlm.nih.gov/pubmed/13947829
work_keys_str_mv AT gilbertvernee reductionofserumcomplementinrabbitsafterinjectionofendotoxin
AT braudeabrahami reductionofserumcomplementinrabbitsafterinjectionofendotoxin

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