PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY : IV. TRANSPLANTATION ANTIBODY FROM EXTRACTS OF SENSITIZED LYMPHOID CELLS

Passive transfer of homograft immunity was successfully achieved by injection of the supernatant obtained from tissue-sensitized lymphoid cells disrupted by sonic vibration. The effective substance destroyed specific skin homografts within 6 days but did not reject non-specific skin grafts in this t...

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Detalles Bibliográficos
Autores principales: Najarian, J. S., Feldman, J. D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1963
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137677/
https://www.ncbi.nlm.nih.gov/pubmed/14087620
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author Najarian, J. S.
Feldman, J. D.
author_facet Najarian, J. S.
Feldman, J. D.
author_sort Najarian, J. S.
collection PubMed
description Passive transfer of homograft immunity was successfully achieved by injection of the supernatant obtained from tissue-sensitized lymphoid cells disrupted by sonic vibration. The effective substance destroyed specific skin homografts within 6 days but did not reject non-specific skin grafts in this time. No evidence of transferred antigen or of transfer factor was found when the effective material was passed to irradiated recipients carrying test grafts. By a variety of physiochemical procedures the "soluble substance" behaved like a gamma globulin and was considered to be a transplantation antibody.
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spelling pubmed-21376772008-04-17 PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY : IV. TRANSPLANTATION ANTIBODY FROM EXTRACTS OF SENSITIZED LYMPHOID CELLS Najarian, J. S. Feldman, J. D. J Exp Med Article Passive transfer of homograft immunity was successfully achieved by injection of the supernatant obtained from tissue-sensitized lymphoid cells disrupted by sonic vibration. The effective substance destroyed specific skin homografts within 6 days but did not reject non-specific skin grafts in this time. No evidence of transferred antigen or of transfer factor was found when the effective material was passed to irradiated recipients carrying test grafts. By a variety of physiochemical procedures the "soluble substance" behaved like a gamma globulin and was considered to be a transplantation antibody. The Rockefeller University Press 1963-10-31 /pmc/articles/PMC2137677/ /pubmed/14087620 Text en Copyright © 1963, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Najarian, J. S.
Feldman, J. D.
PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY : IV. TRANSPLANTATION ANTIBODY FROM EXTRACTS OF SENSITIZED LYMPHOID CELLS
title PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY : IV. TRANSPLANTATION ANTIBODY FROM EXTRACTS OF SENSITIZED LYMPHOID CELLS
title_full PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY : IV. TRANSPLANTATION ANTIBODY FROM EXTRACTS OF SENSITIZED LYMPHOID CELLS
title_fullStr PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY : IV. TRANSPLANTATION ANTIBODY FROM EXTRACTS OF SENSITIZED LYMPHOID CELLS
title_full_unstemmed PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY : IV. TRANSPLANTATION ANTIBODY FROM EXTRACTS OF SENSITIZED LYMPHOID CELLS
title_short PASSIVE TRANSFER OF TRANSPLANTATION IMMUNITY : IV. TRANSPLANTATION ANTIBODY FROM EXTRACTS OF SENSITIZED LYMPHOID CELLS
title_sort passive transfer of transplantation immunity : iv. transplantation antibody from extracts of sensitized lymphoid cells
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137677/
https://www.ncbi.nlm.nih.gov/pubmed/14087620
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