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Oncogenic signaling: new insights and controversies from chronic myeloid leukemia
Chronic myeloid leukemia (CML), which is caused by the BCR–ABL fusion tyrosine kinase, is one of the most intensively studied human cancers. ABL kinase inhibitors have been spectacularly successful in treating CML, but disease persistence and acquired drug resistance can prevent eradication and cure...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137897/ https://www.ncbi.nlm.nih.gov/pubmed/17353369 http://dx.doi.org/10.1084/jem.20062335 |