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Smad4 is critical for self-renewal of hematopoietic stem cells

Members of the transforming growth factor β (TGF-β) superfamily of growth factors have been shown to regulate the in vitro proliferation and maintenance of hematopoietic stem cells (HSCs). Working at a common level of convergence for all TGF-β superfamily signals, Smad4 is key in orchestrating these...

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Detalles Bibliográficos
Autores principales:	Karlsson, Göran, Blank, Ulrika, Moody, Jennifer L., Ehinger, Mats, Singbrant, Sofie, Deng, Chu-Xia, Karlsson, Stefan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137898/ https://www.ncbi.nlm.nih.gov/pubmed/17353364 http://dx.doi.org/10.1084/jem.20060465

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