Roles of peroxiredoxin II in the regulation of proinflammatory responses to LPS and protection against endotoxin-induced lethal shock

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Mammalian 2-Cys peroxiredoxin II (Prx II) is a cellular peroxidase that eliminates endogenous H(2)O(2). The involvement of Prx II in the regulation of lipopolysaccharide (LPS) signaling is poorly understood. In this report, we show that LPS induces substantially enhanced inflammatory events, which i...

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Detalles Bibliográficos
Autores principales: Yang, Chul-Su, Lee, Dong-Seok, Song, Chang-Hwa, An, Se-Jin, Li, Shengjin, Kim, Jin-Man, Kim, Cuk Seong, Yoo, Dae Goon, Jeon, Byeong Hwa, Yang, Hee-Young, Lee, Tae-Hoon, Lee, Zee-Won, El-Benna, Jamel, Yu, Dae-Yeul, Jo, Eun-Kyeong
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137909/
https://www.ncbi.nlm.nih.gov/pubmed/17325201
http://dx.doi.org/10.1084/jem.20061849
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