Cargando…

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell–like diffuse large B cell lymphoma

To elucidate the mechanisms underlying chromosomal translocations in diffuse large B cell lymphoma (DLBCL), we investigated the nature and extent of immunoglobulin class switch recombination (CSR) in these tumors. We used Southern blotting to detect legitimate and illegitimate CSR events in tumor sa...

Descripción completa

Detalles Bibliográficos
Autores principales: Lenz, Georg, Nagel, Inga, Siebert, Reiner, Roschke, Anna V., Sanger, Warren, Wright, George W., Dave, Sandeep S., Tan, Bruce, Zhao, Hong, Rosenwald, Andreas, Muller-Hermelink, Hans Konrad, Gascoyne, Randy D., Campo, Elias, Jaffe, Elaine S., Smeland, Erlend B., Fisher, Richard I., Kuehl, W. Michael, Chan, Wing C., Staudt, Louis M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137913/
https://www.ncbi.nlm.nih.gov/pubmed/17353367
http://dx.doi.org/10.1084/jem.20062041