Cargando…
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion
The contribution of proliferation to B lymphocyte homeostasis and antigen responses is largely unknown. We quantified the replication history of mouse and human B lymphocyte subsets by calculating the ratio between genomic coding joints and signal joints on kappa-deleting recombination excision circ...
Autores principales: | van Zelm, Menno C., Szczepański, Tomasz, van der Burg, Mirjam, van Dongen, Jacques J.M. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137914/ https://www.ncbi.nlm.nih.gov/pubmed/17312005 http://dx.doi.org/10.1084/jem.20060964 |
Ejemplares similares
-
Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age
por: de Jong, Britt G, et al.
Publicado: (2017) -
Quantification of T-Cell and B-Cell Replication History in Aging, Immunodeficiency, and Newborn Screening
por: Verstegen, Ruud H. J., et al.
Publicado: (2019) -
PID Comes Full Circle: Applications of V(D)J Recombination Excision Circles in Research, Diagnostics and Newborn Screening of Primary Immunodeficiency Disorders
por: van Zelm, Menno C., et al.
Publicado: (2011) -
The nature of circulating CD27(+)CD43(+) B cells
por: Perez-Andres, Martin, et al.
Publicado: (2011) -
Clinical Spectrum of SCID: The Key is in the Thymus?
por: van der Burg, Mirjam, et al.
Publicado: (2014)