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Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell–mediated liver damage

Hepatitis B virus (HBV) causes chronic infection in more than 350 million people worldwide. It replicates in hepatocytes but is non-cytopathic; liver damage is thought to be immune mediated. Here, we investigated the role of innate immune responses in mediating liver damage in patients with chronic...

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Detalles Bibliográficos
Autores principales: Dunn, Claire, Brunetto, Maurizia, Reynolds, Gary, Christophides, Theodoros, Kennedy, Patrick T., Lampertico, Pietro, Das, Abhishek, Lopes, A. Ross, Borrow, Persephone, Williams, Kevin, Humphreys, Elizabeth, Afford, Simon, Adams, David H., Bertoletti, Antonio, Maini, Mala K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137916/
https://www.ncbi.nlm.nih.gov/pubmed/17353365
http://dx.doi.org/10.1084/jem.20061287