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ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY-FORMING CELLS AFTER ANTIGEN
Within 5 hours after the intravenous injection of particulate antigen into the primarily immunized mouse, precursors of antibody-forming cells began DNA synthesis as shown by the incorporation of tritium-labeled thymidine. DNA synthesis continued for at least 24 hours and essentially stopped by 48 h...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1965
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137966/ https://www.ncbi.nlm.nih.gov/pubmed/14253479 |
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author | Cohen, Edward P. Talmage, David W. |
author_facet | Cohen, Edward P. Talmage, David W. |
author_sort | Cohen, Edward P. |
collection | PubMed |
description | Within 5 hours after the intravenous injection of particulate antigen into the primarily immunized mouse, precursors of antibody-forming cells began DNA synthesis as shown by the incorporation of tritium-labeled thymidine. DNA synthesis continued for at least 24 hours and essentially stopped by 48 hours. No DNA synthesis in antibody-forming precursor cells occurred before the injection of antigen. |
format | Text |
id | pubmed-2137966 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1965 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21379662008-04-17 ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY-FORMING CELLS AFTER ANTIGEN Cohen, Edward P. Talmage, David W. J Exp Med Article Within 5 hours after the intravenous injection of particulate antigen into the primarily immunized mouse, precursors of antibody-forming cells began DNA synthesis as shown by the incorporation of tritium-labeled thymidine. DNA synthesis continued for at least 24 hours and essentially stopped by 48 hours. No DNA synthesis in antibody-forming precursor cells occurred before the injection of antigen. The Rockefeller University Press 1965-01-01 /pmc/articles/PMC2137966/ /pubmed/14253479 Text en Copyright © 1965 by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Cohen, Edward P. Talmage, David W. ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY-FORMING CELLS AFTER ANTIGEN |
title | ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY-FORMING CELLS AFTER ANTIGEN |
title_full | ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY-FORMING CELLS AFTER ANTIGEN |
title_fullStr | ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY-FORMING CELLS AFTER ANTIGEN |
title_full_unstemmed | ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY-FORMING CELLS AFTER ANTIGEN |
title_short | ONSET AND DURATION OF DNA SYNTHESIS IN ANTIBODY-FORMING CELLS AFTER ANTIGEN |
title_sort | onset and duration of dna synthesis in antibody-forming cells after antigen |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137966/ https://www.ncbi.nlm.nih.gov/pubmed/14253479 |
work_keys_str_mv | AT cohenedwardp onsetanddurationofdnasynthesisinantibodyformingcellsafterantigen AT talmagedavidw onsetanddurationofdnasynthesisinantibodyformingcellsafterantigen |