IMMUNOLOGIC RELATIONS AMONG VARIOUS ANIMAL COLLAGENS

By the use of complement fixation and in vivo immunofluorescence with cross-absorption studies it was shown that acid soluble collagens prepared from rat, mouse, guinea pig, chicken, carp, and man exhibit species specificity. Rat and mouse collagens were found to be indistinguishable and to cross-re...

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Detalles Bibliográficos
Autores principales: Rothbard, Sidney, Watson, Robert F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1965
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138071/
https://www.ncbi.nlm.nih.gov/pubmed/5320302
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author Rothbard, Sidney
Watson, Robert F.
author_facet Rothbard, Sidney
Watson, Robert F.
author_sort Rothbard, Sidney
collection PubMed
description By the use of complement fixation and in vivo immunofluorescence with cross-absorption studies it was shown that acid soluble collagens prepared from rat, mouse, guinea pig, chicken, carp, and man exhibit species specificity. Rat and mouse collagens were found to be indistinguishable and to cross-react with guinea pig collagen. Cross-reactions also occurred between the collagens of rat and man and chicken and man. Tissue specificity, or an antigen common to all of the collagens, was not demonstrated. There was complete agreement in the results of the two immunologic methods. The findings in this study support the conclusion that collagen in some form is present in the renal glomerular basement membranes.
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spelling pubmed-21380712008-04-17 IMMUNOLOGIC RELATIONS AMONG VARIOUS ANIMAL COLLAGENS Rothbard, Sidney Watson, Robert F. J Exp Med Article By the use of complement fixation and in vivo immunofluorescence with cross-absorption studies it was shown that acid soluble collagens prepared from rat, mouse, guinea pig, chicken, carp, and man exhibit species specificity. Rat and mouse collagens were found to be indistinguishable and to cross-react with guinea pig collagen. Cross-reactions also occurred between the collagens of rat and man and chicken and man. Tissue specificity, or an antigen common to all of the collagens, was not demonstrated. There was complete agreement in the results of the two immunologic methods. The findings in this study support the conclusion that collagen in some form is present in the renal glomerular basement membranes. The Rockefeller University Press 1965-09-01 /pmc/articles/PMC2138071/ /pubmed/5320302 Text en Copyright © 1965 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Rothbard, Sidney
Watson, Robert F.
IMMUNOLOGIC RELATIONS AMONG VARIOUS ANIMAL COLLAGENS
title IMMUNOLOGIC RELATIONS AMONG VARIOUS ANIMAL COLLAGENS
title_full IMMUNOLOGIC RELATIONS AMONG VARIOUS ANIMAL COLLAGENS
title_fullStr IMMUNOLOGIC RELATIONS AMONG VARIOUS ANIMAL COLLAGENS
title_full_unstemmed IMMUNOLOGIC RELATIONS AMONG VARIOUS ANIMAL COLLAGENS
title_short IMMUNOLOGIC RELATIONS AMONG VARIOUS ANIMAL COLLAGENS
title_sort immunologic relations among various animal collagens
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138071/
https://www.ncbi.nlm.nih.gov/pubmed/5320302
work_keys_str_mv AT rothbardsidney immunologicrelationsamongvariousanimalcollagens
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