INCREASED VASCULAR PERMEABILITY INDUCED BY HUMAN PLASMIN

Preparations of plasminogen, soluble in aqueous media, increased vascular permeability in guinea pig skin when activated by streptokinase or urokinase. The permeability-enhancing effect was inhibited by soybean trypsin inhibitor but not by triprolidine. Permeability-enhancing activity evolved when p...

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Detalles Bibliográficos
Autor principal: Ratnoff, Oscar D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1965
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138110/
https://www.ncbi.nlm.nih.gov/pubmed/19867295
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author Ratnoff, Oscar D.
author_facet Ratnoff, Oscar D.
author_sort Ratnoff, Oscar D.
collection PubMed
description Preparations of plasminogen, soluble in aqueous media, increased vascular permeability in guinea pig skin when activated by streptokinase or urokinase. The permeability-enhancing effect was inhibited by soybean trypsin inhibitor but not by triprolidine. Permeability-enhancing activity evolved when plasmin was incubated with fractions of plasma rich in prokinin. The experiments described suggest that plasmin exerts its permeability-increasing effect through the elaboration of kinins.
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spelling pubmed-21381102008-04-17 INCREASED VASCULAR PERMEABILITY INDUCED BY HUMAN PLASMIN Ratnoff, Oscar D. J Exp Med Article Preparations of plasminogen, soluble in aqueous media, increased vascular permeability in guinea pig skin when activated by streptokinase or urokinase. The permeability-enhancing effect was inhibited by soybean trypsin inhibitor but not by triprolidine. Permeability-enhancing activity evolved when plasmin was incubated with fractions of plasma rich in prokinin. The experiments described suggest that plasmin exerts its permeability-increasing effect through the elaboration of kinins. The Rockefeller University Press 1965-10-31 /pmc/articles/PMC2138110/ /pubmed/19867295 Text en Copyright © 1965 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Ratnoff, Oscar D.
INCREASED VASCULAR PERMEABILITY INDUCED BY HUMAN PLASMIN
title INCREASED VASCULAR PERMEABILITY INDUCED BY HUMAN PLASMIN
title_full INCREASED VASCULAR PERMEABILITY INDUCED BY HUMAN PLASMIN
title_fullStr INCREASED VASCULAR PERMEABILITY INDUCED BY HUMAN PLASMIN
title_full_unstemmed INCREASED VASCULAR PERMEABILITY INDUCED BY HUMAN PLASMIN
title_short INCREASED VASCULAR PERMEABILITY INDUCED BY HUMAN PLASMIN
title_sort increased vascular permeability induced by human plasmin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138110/
https://www.ncbi.nlm.nih.gov/pubmed/19867295
work_keys_str_mv AT ratnoffoscard increasedvascularpermeabilityinducedbyhumanplasmin

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