Cargando…
THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES
Electron microscopic and other evidence have provided support for the hypothesis that the sickling phenomenon is due to the intracellular formation of long slender crystals of reduced sickle hemoglobin. The rapid growth of these crystals causing tenting of the cell membrane is responsible for the bi...
Autor principal: | |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1966
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138140/ https://www.ncbi.nlm.nih.gov/pubmed/5905245 |
_version_ | 1782143493800460288 |
---|---|
author | Stetson, Chandler A. |
author_facet | Stetson, Chandler A. |
author_sort | Stetson, Chandler A. |
collection | PubMed |
description | Electron microscopic and other evidence have provided support for the hypothesis that the sickling phenomenon is due to the intracellular formation of long slender crystals of reduced sickle hemoglobin. The rapid growth of these crystals causing tenting of the cell membrane is responsible for the bizarre distortion of the erythrocytes and presumably for the disease itself. |
format | Text |
id | pubmed-2138140 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1966 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21381402008-04-17 THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES Stetson, Chandler A. J Exp Med Article Electron microscopic and other evidence have provided support for the hypothesis that the sickling phenomenon is due to the intracellular formation of long slender crystals of reduced sickle hemoglobin. The rapid growth of these crystals causing tenting of the cell membrane is responsible for the bizarre distortion of the erythrocytes and presumably for the disease itself. The Rockefeller University Press 1966-01-31 /pmc/articles/PMC2138140/ /pubmed/5905245 Text en Copyright © 1966 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Stetson, Chandler A. THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES |
title | THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES |
title_full | THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES |
title_fullStr | THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES |
title_full_unstemmed | THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES |
title_short | THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES |
title_sort | state of hemoglobin in sickled erythrocytes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138140/ https://www.ncbi.nlm.nih.gov/pubmed/5905245 |
work_keys_str_mv | AT stetsonchandlera thestateofhemoglobininsicklederythrocytes AT stetsonchandlera stateofhemoglobininsicklederythrocytes |