OCCURRENCE AND PROPERTIES OF A MACROGLOBULIN DIMER IN SOME HYPERGLOBULINEMIC SERA

A 22S human γM-globulin component has been subjected to various study. It appears to be a dimer of 19S proteins and can undergo reversible molecular transitions which are both pH and temperature dependent. The 22S material regenerated from its 8S subunits no longer undergo similar transformations. E...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, T., Deutsch, H. F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1966
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138266/
https://www.ncbi.nlm.nih.gov/pubmed/4959011
_version_ 1782143523271737344
author Suzuki, T.
Deutsch, H. F.
author_facet Suzuki, T.
Deutsch, H. F.
author_sort Suzuki, T.
collection PubMed
description A 22S human γM-globulin component has been subjected to various study. It appears to be a dimer of 19S proteins and can undergo reversible molecular transitions which are both pH and temperature dependent. The 22S material regenerated from its 8S subunits no longer undergo similar transformations. Efforts to demonstrate that the 22S material was an antigen-antibody complex of 19S molecules were unsuccessful. Complex precipitin reactions in gels are given by macroglobulins containing this component with antibody to L chains.
format Text
id pubmed-2138266
institution National Center for Biotechnology Information
language English
publishDate 1966
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21382662008-04-17 OCCURRENCE AND PROPERTIES OF A MACROGLOBULIN DIMER IN SOME HYPERGLOBULINEMIC SERA Suzuki, T. Deutsch, H. F. J Exp Med Article A 22S human γM-globulin component has been subjected to various study. It appears to be a dimer of 19S proteins and can undergo reversible molecular transitions which are both pH and temperature dependent. The 22S material regenerated from its 8S subunits no longer undergo similar transformations. Efforts to demonstrate that the 22S material was an antigen-antibody complex of 19S molecules were unsuccessful. Complex precipitin reactions in gels are given by macroglobulins containing this component with antibody to L chains. The Rockefeller University Press 1966-10-31 /pmc/articles/PMC2138266/ /pubmed/4959011 Text en Copyright © 1966 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Suzuki, T.
Deutsch, H. F.
OCCURRENCE AND PROPERTIES OF A MACROGLOBULIN DIMER IN SOME HYPERGLOBULINEMIC SERA
title OCCURRENCE AND PROPERTIES OF A MACROGLOBULIN DIMER IN SOME HYPERGLOBULINEMIC SERA
title_full OCCURRENCE AND PROPERTIES OF A MACROGLOBULIN DIMER IN SOME HYPERGLOBULINEMIC SERA
title_fullStr OCCURRENCE AND PROPERTIES OF A MACROGLOBULIN DIMER IN SOME HYPERGLOBULINEMIC SERA
title_full_unstemmed OCCURRENCE AND PROPERTIES OF A MACROGLOBULIN DIMER IN SOME HYPERGLOBULINEMIC SERA
title_short OCCURRENCE AND PROPERTIES OF A MACROGLOBULIN DIMER IN SOME HYPERGLOBULINEMIC SERA
title_sort occurrence and properties of a macroglobulin dimer in some hyperglobulinemic sera
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138266/
https://www.ncbi.nlm.nih.gov/pubmed/4959011
work_keys_str_mv AT suzukit occurrenceandpropertiesofamacroglobulindimerinsomehyperglobulinemicsera
AT deutschhf occurrenceandpropertiesofamacroglobulindimerinsomehyperglobulinemicsera

Ejemplares similares