AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : VII. AN ATTEMPT TO DETERMINE WHETHER THE MATERIAL RESPONSIBLE FOR THE ANTIPASSIVE IMMUNITY EFFECT EXHIBITED BY MICE INJECTED WITH HELENINE IS AN INTERFERON

Helenine, NDV, and statolon, all known inducers of interferon in mice, all exerted a marked antiviral effect against Semliki Forest virus. This AV effect was, so far as can be demonstrated, mediated through, the induced interferon. The same three materials also exerted a marked antipassive immunity...

Descripción completa

Detalles Bibliográficos
Autor principal: Shope, Richard E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1966
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138268/
https://www.ncbi.nlm.nih.gov/pubmed/5926302
_version_ 1782143523745693696
author Shope, Richard E.
author_facet Shope, Richard E.
author_sort Shope, Richard E.
collection PubMed
description Helenine, NDV, and statolon, all known inducers of interferon in mice, all exerted a marked antiviral effect against Semliki Forest virus. This AV effect was, so far as can be demonstrated, mediated through, the induced interferon. The same three materials also exerted a marked antipassive immunity effect. All the evidence that can be brought to bear indicates that this API effect like the AV effect is mediated through interferon known to be induced by the three materials. If the API effect does indeed have interferon as its basis, this represents a new and totally unsuspected action of interferon.
format Text
id pubmed-2138268
institution National Center for Biotechnology Information
language English
publishDate 1966
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21382682008-04-17 AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : VII. AN ATTEMPT TO DETERMINE WHETHER THE MATERIAL RESPONSIBLE FOR THE ANTIPASSIVE IMMUNITY EFFECT EXHIBITED BY MICE INJECTED WITH HELENINE IS AN INTERFERON Shope, Richard E. J Exp Med Article Helenine, NDV, and statolon, all known inducers of interferon in mice, all exerted a marked antiviral effect against Semliki Forest virus. This AV effect was, so far as can be demonstrated, mediated through, the induced interferon. The same three materials also exerted a marked antipassive immunity effect. All the evidence that can be brought to bear indicates that this API effect like the AV effect is mediated through interferon known to be induced by the three materials. If the API effect does indeed have interferon as its basis, this represents a new and totally unsuspected action of interferon. The Rockefeller University Press 1966-10-31 /pmc/articles/PMC2138268/ /pubmed/5926302 Text en Copyright © 1966 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Shope, Richard E.
AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : VII. AN ATTEMPT TO DETERMINE WHETHER THE MATERIAL RESPONSIBLE FOR THE ANTIPASSIVE IMMUNITY EFFECT EXHIBITED BY MICE INJECTED WITH HELENINE IS AN INTERFERON
title AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : VII. AN ATTEMPT TO DETERMINE WHETHER THE MATERIAL RESPONSIBLE FOR THE ANTIPASSIVE IMMUNITY EFFECT EXHIBITED BY MICE INJECTED WITH HELENINE IS AN INTERFERON
title_full AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : VII. AN ATTEMPT TO DETERMINE WHETHER THE MATERIAL RESPONSIBLE FOR THE ANTIPASSIVE IMMUNITY EFFECT EXHIBITED BY MICE INJECTED WITH HELENINE IS AN INTERFERON
title_fullStr AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : VII. AN ATTEMPT TO DETERMINE WHETHER THE MATERIAL RESPONSIBLE FOR THE ANTIPASSIVE IMMUNITY EFFECT EXHIBITED BY MICE INJECTED WITH HELENINE IS AN INTERFERON
title_full_unstemmed AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : VII. AN ATTEMPT TO DETERMINE WHETHER THE MATERIAL RESPONSIBLE FOR THE ANTIPASSIVE IMMUNITY EFFECT EXHIBITED BY MICE INJECTED WITH HELENINE IS AN INTERFERON
title_short AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM : VII. AN ATTEMPT TO DETERMINE WHETHER THE MATERIAL RESPONSIBLE FOR THE ANTIPASSIVE IMMUNITY EFFECT EXHIBITED BY MICE INJECTED WITH HELENINE IS AN INTERFERON
title_sort antiviral substance from penicillium funiculosum : vii. an attempt to determine whether the material responsible for the antipassive immunity effect exhibited by mice injected with helenine is an interferon
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138268/
https://www.ncbi.nlm.nih.gov/pubmed/5926302
work_keys_str_mv AT shopericharde anantiviralsubstancefrompenicilliumfuniculosumviianattempttodeterminewhetherthematerialresponsiblefortheantipassiveimmunityeffectexhibitedbymiceinjectedwithhelenineisaninterferon
AT shopericharde antiviralsubstancefrompenicilliumfuniculosumviianattempttodeterminewhetherthematerialresponsiblefortheantipassiveimmunityeffectexhibitedbymiceinjectedwithhelenineisaninterferon

Ejemplares similares