HYBRID FORMATION BETWEEN BACTERIAL ENDOTOXINS

When endotoxins extracted from enteric bacteria were mixed in the presence of sodium deoxycholate, and the bile salt was subsequently removed by dialysis or by extraction with ethanol, a new type of endotoxin was formed. The latter material was as biologically active as the original endotoxins and p...

Descripción completa

Detalles Bibliográficos
Autores principales: Rudbach, Jon A., Milner, Kelsey C., Ribi, Edgar
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1967
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138301/
https://www.ncbi.nlm.nih.gov/pubmed/4961269
_version_ 1782143531460067328
author Rudbach, Jon A.
Milner, Kelsey C.
Ribi, Edgar
author_facet Rudbach, Jon A.
Milner, Kelsey C.
Ribi, Edgar
author_sort Rudbach, Jon A.
collection PubMed
description When endotoxins extracted from enteric bacteria were mixed in the presence of sodium deoxycholate, and the bile salt was subsequently removed by dialysis or by extraction with ethanol, a new type of endotoxin was formed. The latter material was as biologically active as the original endotoxins and possessed a combination of antigenic determinants that were previously unique to each of the individual endotoxins in the mixture. This hybrid formation between endotoxins was detected by immunodiffusion and radioautography and by quantitative precipitation procedures.
format Text
id pubmed-2138301
institution National Center for Biotechnology Information
language English
publishDate 1967
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21383012008-04-17 HYBRID FORMATION BETWEEN BACTERIAL ENDOTOXINS Rudbach, Jon A. Milner, Kelsey C. Ribi, Edgar J Exp Med Article When endotoxins extracted from enteric bacteria were mixed in the presence of sodium deoxycholate, and the bile salt was subsequently removed by dialysis or by extraction with ethanol, a new type of endotoxin was formed. The latter material was as biologically active as the original endotoxins and possessed a combination of antigenic determinants that were previously unique to each of the individual endotoxins in the mixture. This hybrid formation between endotoxins was detected by immunodiffusion and radioautography and by quantitative precipitation procedures. The Rockefeller University Press 1967-07-01 /pmc/articles/PMC2138301/ /pubmed/4961269 Text en Copyright © 1967 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Rudbach, Jon A.
Milner, Kelsey C.
Ribi, Edgar
HYBRID FORMATION BETWEEN BACTERIAL ENDOTOXINS
title HYBRID FORMATION BETWEEN BACTERIAL ENDOTOXINS
title_full HYBRID FORMATION BETWEEN BACTERIAL ENDOTOXINS
title_fullStr HYBRID FORMATION BETWEEN BACTERIAL ENDOTOXINS
title_full_unstemmed HYBRID FORMATION BETWEEN BACTERIAL ENDOTOXINS
title_short HYBRID FORMATION BETWEEN BACTERIAL ENDOTOXINS
title_sort hybrid formation between bacterial endotoxins
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138301/
https://www.ncbi.nlm.nih.gov/pubmed/4961269
work_keys_str_mv AT rudbachjona hybridformationbetweenbacterialendotoxins
AT milnerkelseyc hybridformationbetweenbacterialendotoxins
AT ribiedgar hybridformationbetweenbacterialendotoxins

Ejemplares similares