STUDIES ON THE NONSPECIFIC DEPRESSION OF THE IMMUNE RESPONSE

Calf serum has been shown to suppress the primary immune response to erythrocytes and some bacterial antigens in mice if administered prior to and not after immunization. The importance of the route of iniection of antigens and immunosuppressant is indicated. It is suggested that immunosuppression i...

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Detalles Bibliográficos
Autores principales: Jennings, John F., Oates, Carolyn M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1967
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138386/
https://www.ncbi.nlm.nih.gov/pubmed/6055757
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author Jennings, John F.
Oates, Carolyn M.
author_facet Jennings, John F.
Oates, Carolyn M.
author_sort Jennings, John F.
collection PubMed
description Calf serum has been shown to suppress the primary immune response to erythrocytes and some bacterial antigens in mice if administered prior to and not after immunization. The importance of the route of iniection of antigens and immunosuppressant is indicated. It is suggested that immunosuppression is achieved by phagocytosis and enyzmatic destruction of the injected antigen by peritoneal macrophages. A similar mechanism is probably involved in the type of immunosuppression induced by PHA.
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spelling pubmed-21383862008-04-17 STUDIES ON THE NONSPECIFIC DEPRESSION OF THE IMMUNE RESPONSE Jennings, John F. Oates, Carolyn M. J Exp Med Article Calf serum has been shown to suppress the primary immune response to erythrocytes and some bacterial antigens in mice if administered prior to and not after immunization. The importance of the route of iniection of antigens and immunosuppressant is indicated. It is suggested that immunosuppression is achieved by phagocytosis and enyzmatic destruction of the injected antigen by peritoneal macrophages. A similar mechanism is probably involved in the type of immunosuppression induced by PHA. The Rockefeller University Press 1967-10-01 /pmc/articles/PMC2138386/ /pubmed/6055757 Text en Copyright © 1967 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Jennings, John F.
Oates, Carolyn M.
STUDIES ON THE NONSPECIFIC DEPRESSION OF THE IMMUNE RESPONSE
title STUDIES ON THE NONSPECIFIC DEPRESSION OF THE IMMUNE RESPONSE
title_full STUDIES ON THE NONSPECIFIC DEPRESSION OF THE IMMUNE RESPONSE
title_fullStr STUDIES ON THE NONSPECIFIC DEPRESSION OF THE IMMUNE RESPONSE
title_full_unstemmed STUDIES ON THE NONSPECIFIC DEPRESSION OF THE IMMUNE RESPONSE
title_short STUDIES ON THE NONSPECIFIC DEPRESSION OF THE IMMUNE RESPONSE
title_sort studies on the nonspecific depression of the immune response
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138386/
https://www.ncbi.nlm.nih.gov/pubmed/6055757
work_keys_str_mv AT jenningsjohnf studiesonthenonspecificdepressionoftheimmuneresponse
AT oatescarolynm studiesonthenonspecificdepressionoftheimmuneresponse

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