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EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS
Experiments utilizing chromosome marker and histological techniques in combination with parabiosis and transplanatation procedures have demonstrated an inflow of blood-home stem cells into the chick embryo thymic rudiment. There is close similarity between the histological picture in the chick and i...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1967
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138391/ https://www.ncbi.nlm.nih.gov/pubmed/4861748 |
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author | Moore, M. A. S. Owen, J. J. T. |
author_facet | Moore, M. A. S. Owen, J. J. T. |
author_sort | Moore, M. A. S. |
collection | PubMed |
description | Experiments utilizing chromosome marker and histological techniques in combination with parabiosis and transplanatation procedures have demonstrated an inflow of blood-home stem cells into the chick embryo thymic rudiment. There is close similarity between the histological picture in the chick and in the mouse thymic rudiment, and it is proposed that a similar developmental process takes place in both. It may be concluded that the epithelial component of the thymic rudiment, rather than producing lymphoid cells itself, furnishes an inductive environment for the proliferation and differentiation of stem cells derived extrinsically. |
format | Text |
id | pubmed-2138391 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1967 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21383912008-04-17 EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS Moore, M. A. S. Owen, J. J. T. J Exp Med Article Experiments utilizing chromosome marker and histological techniques in combination with parabiosis and transplanatation procedures have demonstrated an inflow of blood-home stem cells into the chick embryo thymic rudiment. There is close similarity between the histological picture in the chick and in the mouse thymic rudiment, and it is proposed that a similar developmental process takes place in both. It may be concluded that the epithelial component of the thymic rudiment, rather than producing lymphoid cells itself, furnishes an inductive environment for the proliferation and differentiation of stem cells derived extrinsically. The Rockefeller University Press 1967-10-01 /pmc/articles/PMC2138391/ /pubmed/4861748 Text en Copyright © 1967 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Moore, M. A. S. Owen, J. J. T. EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS |
title | EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS |
title_full | EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS |
title_fullStr | EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS |
title_full_unstemmed | EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS |
title_short | EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS |
title_sort | experimental studies on the development of the thymus |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138391/ https://www.ncbi.nlm.nih.gov/pubmed/4861748 |
work_keys_str_mv | AT mooremas experimentalstudiesonthedevelopmentofthethymus AT owenjjt experimentalstudiesonthedevelopmentofthethymus |