CELLULAR KINETICS ASSOCIATED WITH THE DEVELOPMENT OF ACQUIRED CELLULAR RESISTANCE

Mice infected with either BCG or Listeria monocytogenes display the same type of cellular response pattern. In both infections there is an intense proliferation of splenic lymphoid cells, a coincident proliferation of differentiated macrophages, and a subsequent production of macrophages with increa...

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Detalles Bibliográficos
Autor principal: North, Robert J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1969
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138681/
https://www.ncbi.nlm.nih.gov/pubmed/4978533
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author North, Robert J.
author_facet North, Robert J.
author_sort North, Robert J.
collection PubMed
description Mice infected with either BCG or Listeria monocytogenes display the same type of cellular response pattern. In both infections there is an intense proliferation of splenic lymphoid cells, a coincident proliferation of differentiated macrophages, and a subsequent production of macrophages with increased metabolic potential. The temporal relations between these events and the onset of host resistance indicate that lymphoid cell proliferation and macrophage proliferation are essential events in the response which leads to cellular resistance against facultative intracellular parasites.
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spelling pubmed-21386812008-04-17 CELLULAR KINETICS ASSOCIATED WITH THE DEVELOPMENT OF ACQUIRED CELLULAR RESISTANCE North, Robert J. J Exp Med Article Mice infected with either BCG or Listeria monocytogenes display the same type of cellular response pattern. In both infections there is an intense proliferation of splenic lymphoid cells, a coincident proliferation of differentiated macrophages, and a subsequent production of macrophages with increased metabolic potential. The temporal relations between these events and the onset of host resistance indicate that lymphoid cell proliferation and macrophage proliferation are essential events in the response which leads to cellular resistance against facultative intracellular parasites. The Rockefeller University Press 1969-08-01 /pmc/articles/PMC2138681/ /pubmed/4978533 Text en Copyright © 1969 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
North, Robert J.
CELLULAR KINETICS ASSOCIATED WITH THE DEVELOPMENT OF ACQUIRED CELLULAR RESISTANCE
title CELLULAR KINETICS ASSOCIATED WITH THE DEVELOPMENT OF ACQUIRED CELLULAR RESISTANCE
title_full CELLULAR KINETICS ASSOCIATED WITH THE DEVELOPMENT OF ACQUIRED CELLULAR RESISTANCE
title_fullStr CELLULAR KINETICS ASSOCIATED WITH THE DEVELOPMENT OF ACQUIRED CELLULAR RESISTANCE
title_full_unstemmed CELLULAR KINETICS ASSOCIATED WITH THE DEVELOPMENT OF ACQUIRED CELLULAR RESISTANCE
title_short CELLULAR KINETICS ASSOCIATED WITH THE DEVELOPMENT OF ACQUIRED CELLULAR RESISTANCE
title_sort cellular kinetics associated with the development of acquired cellular resistance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138681/
https://www.ncbi.nlm.nih.gov/pubmed/4978533
work_keys_str_mv AT northrobertj cellularkineticsassociatedwiththedevelopmentofacquiredcellularresistance

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